Ittihad Aleppo 4-2 Kazma SC
| 22.09.2010 | Kazma SC | 0-1 | Ittihad Aleppo | |
| 15.09.2010 | Ittihad Aleppo | 3-2 | Kazma SC | |
Karamah 1-2 Muang Thong United *
| 21.09.2010 | Muang Thong United | 2-0 | Karamah | |
| 14.09.2010 | Karamah | 1-0 | Muang Thong United | |
*Riffa Club 8-3 SHB-Da Nang FC
| 21.09.2010 | SHB-Da Nang FC | 3-5 | Riffa Club | |
| 14.09.2010 | Riffa Club | 3-0 | SHB-Da Nang FC | |
Thai Port FC 0-3 Qadisiya Kuwait *
| 21.09.2010 | Qadisiya Kuwait | 3-0 | Thai Port FC | |
| 14.09.2010 | Thai Port FC | 0-0 | Qadisiya Kuwait | |