Gor Mahia 0-3 Ahly Cairo
| 21.09.2024 | Ahly Cairo | - | Gor Mahia | |
| 15.09.2024 | Gor Mahia | 0-3 | Ahly Cairo | |
AS Douanes (BFA) 1-0 CR Belouizdad
| 20.09.2024 | CR Belouizdad | - | AS Douanes (BFA) | |
| 14.09.2024 | AS Douanes (BFA) | 1-0 | CR Belouizdad | |
AS Maniema Union 2-1 Petro Atlético Luanda
| 21.09.2024 | Petro Atlético Luanda | - | AS Maniema Union | |
| 14.09.2024 | AS Maniema Union | 2-1 | Petro Atlético Luanda | |
CBE SA 0-1 Young Africans
| 21.09.2024 | Young Africans | - | CBE SA | |
| 14.09.2024 | CBE SA | 0-1 | Young Africans | |
Dekedaha FC 1-4 Esperance ST
| 21.09.2024 | Esperance ST | - | Dekedaha FC | |
| 15.09.2024 | Dekedaha FC | 1-4 | Esperance ST | |
Djoliba AC 1-0 ASKO Kara
| 22.09.2024 | ASKO Kara | - | Djoliba AC | |
| 14.09.2024 | Djoliba AC | 1-0 | ASKO Kara | |
Enugu Rangers 1-0 Sagrada Esperanca
| 22.09.2024 | Sagrada Esperanca | - | Enugu Rangers | |
| 13.09.2024 | Enugu Rangers | 1-0 | Sagrada Esperanca | |
Merreikh Al Sudan 2-2 FAR Rabat
| 22.09.2024 | FAR Rabat | - | Merreikh Al Sudan | |
| 14.09.2024 | Merreikh Al Sudan | 2-2 | FAR Rabat | |
FC Samartex 1996 2-2 Raja Casablanca
| 21.09.2024 | Raja Casablanca | - | FC Samartex 1996 | |
| 15.09.2024 | FC Samartex 1996 | 2-2 | Raja Casablanca | |
FC San Pédro 2-2 Al Hilal Al Sudani
| 22.09.2024 | Al Hilal Al Sudani | - | FC San Pédro | |
| 15.09.2024 | FC San Pédro | 2-2 | Al Hilal Al Sudani | |
Mbabane Swallows 0-4 Mamelodi Sundowns
| 21.09.2024 | Mamelodi Sundowns | - | Mbabane Swallows | |
| 14.09.2024 | Mbabane Swallows | 0-4 | Mamelodi Sundowns | |
US Monastir 1-0 MC Alger
| 21.09.2024 | MC Alger | - | US Monastir | |
| 13.09.2024 | US Monastir | 1-0 | MC Alger | |
Jwaneng Galaxy 0-2 Orlando Pirates
| 21.09.2024 | Orlando Pirates | - | Jwaneng Galaxy | |
| 14.09.2024 | Jwaneng Galaxy | 0-2 | Orlando Pirates | |
APR FC 1-1 Pyramids FC
| 21.09.2024 | Pyramids FC | - | APR FC | |
| 14.09.2024 | APR FC | 1-1 | Pyramids FC | |
Red Arrows FC 0-2 TP Mazembe
| 21.09.2024 | TP Mazembe | - | Red Arrows FC | |
| 14.09.2024 | Red Arrows FC | 0-2 | TP Mazembe | |
Stade d'Abidjan 2-0 Milo FC
| 22.09.2024 | Milo FC | - | Stade d'Abidjan | |
| 15.09.2024 | Stade d'Abidjan | 2-0 | Milo FC | |