Merreikh Al Sudan 3-4 ASFAN Niamey
| 31.07.2010 | ASFAN Niamey | 2-1 | Merreikh Al Sudan | |
| 17.07.2010 | Merreikh Al Sudan | 2-2 | ASFAN Niamey | |
Al Hilal Al Sudani 8-1 CAPS United FC
| 01.08.2010 | CAPS United FC | 1-3 | Al Hilal Al Sudani | |
| 18.07.2010 | Al Hilal Al Sudani | 5-0 | CAPS United FC | |
Petro Atlético Luanda 1-3 CS Sfaxien
| 01.08.2010 | CS Sfaxien | 3-1 | Petro Atlético Luanda | |
| 17.07.2010 | Petro Atlético Luanda | 0-0 | CS Sfaxien | |
*Djoliba AC 1-1 CR Belouizdad
| 31.07.2010 | CR Belouizdad | 1-1 | Djoliba AC | |
| 17.07.2010 | Djoliba AC | 0-0 | CR Belouizdad | |
SuperSport United 2-2 FUS Rabat
| 01.08.2010 | FUS Rabat | 1-0 | SuperSport United | |
| 17.07.2010 | SuperSport United | 2-1 | FUS Rabat | |
Gaborone United 2-8 Haras Al Hodoud
| 31.07.2010 | Haras Al Hodoud | 8-1 | Gaborone United | |
| 17.07.2010 | Gaborone United | 1-0 | Haras Al Hodoud | |
Ittihad Tripoli 3-2 1º de Agosto
| 31.07.2010 | 1º de Agosto | 2-1 | Ittihad Tripoli | |
| 16.07.2010 | Ittihad Tripoli | 2-0 | 1º de Agosto | |