*Al Masry SC 2-0 USM Alger
| 23.09.2018 | USM Alger | 0-1 | Al Masry SC | |
| 16.09.2018 | Al Masry SC | 1-0 | USM Alger | |
*AS Vita Club 4-2 Renaissance Berkane
| 23.09.2018 | Renaissance Berkane | 1-1 | AS Vita Club | |
| 16.09.2018 | AS Vita Club | 3-1 | Renaissance Berkane | |
CARA Brazzaville 1-3 Raja Casablanca *
| 23.09.2018 | Raja Casablanca | 1-0 | CARA Brazzaville | |
| 16.09.2018 | CARA Brazzaville | 1-2 | Raja Casablanca | |
Rayon Sports 1-5 Enyimba FC *
| 23.09.2018 | Enyimba FC | 5-1 | Rayon Sports | |
| 16.09.2018 | Rayon Sports | 0-0 | Enyimba FC | |