*São Paulo/SP 8-4 Bolívar
| 31.01.2013 | Bolívar | 4-3 | São Paulo/SP | |
| 24.01.2013 | São Paulo/SP | 5-0 | Bolívar | |
*CA Tigre 5-1 Anzoátegui*
| 29.01.2013 | Anzoátegui* | 0-3 | CA Tigre | |
| 23.01.2013 | CA Tigre | 2-1 | Anzoátegui* | |
*Deportes Tolima 2-1 Cesar Vallejo
| 01.02.2013 | Cesar Vallejo | 1-1 | Deportes Tolima | |
| 25.01.2013 | Deportes Tolima | 1-0 | Cesar Vallejo | |
Defensor Sporting 0-2 Olimpia Asunción *
| 31.01.2013 | Olimpia Asunción | 2-0 | Defensor Sporting | |
| 24.01.2013 | Defensor Sporting | 0-0 | Olimpia Asunción | |
Club León 2-2 Deportes Iquique *
| 30.01.2013 | Deportes Iquique | 1-1/p.4-2 | Club León | |
| 23.01.2013 | Club León | 1-1 | Deportes Iquique | |