*Arsenal FC 2-0 AC Milan
| 04.03.2008 | AC Milan | 0-2 | Arsenal FC | |
| 20.02.2008 | Arsenal FC | 0-0 | AC Milan | |
*AS Roma 4-2 Real Madrid
| 05.03.2008 | Real Madrid | 1-2 | AS Roma | |
| 19.02.2008 | AS Roma | 2-1 | Real Madrid | |
Celtic FC 2-4 FC Barcelona *
| 04.03.2008 | FC Barcelona | 1-0 | Celtic FC | |
| 20.02.2008 | Celtic FC | 2-3 | FC Barcelona | |
*Liverpool 3-0 Inter Milan
| 11.03.2008 | Inter Milan | 0-1 | Liverpool | |
| 19.02.2008 | Liverpool | 2-0 | Inter Milan | |
Lyon 1-2 Manchester United *
| 04.03.2008 | Manchester United | 1-0 | Lyon | |
| 20.02.2008 | Lyon | 1-1 | Manchester United | |
Olympiakos Pireus 0-3 Chelsea FC *
| 05.03.2008 | Chelsea FC | 3-0 | Olympiakos Pireus | |
| 19.02.2008 | Olympiakos Pireus | 0-0 | Chelsea FC | |
*Schalke 04 1-1 FC Porto
| 05.03.2008 | FC Porto | 1-0/p.1-4 | Schalke 04 | |
| 19.02.2008 | Schalke 04 | 1-0 | FC Porto | |
*Fenerbahçe SK 5-5 Sevilla FC
| 04.03.2008 | Sevilla FC | 3-2/p.2-3 | Fenerbahçe SK | |
| 20.02.2008 | Fenerbahçe SK | 3-2 | Sevilla FC | |