*Lyon 8-2 Anderlecht
| 25.08.2009 | Anderlecht | 1-3 | Lyon | |
| 19.08.2009 | Lyon | 5-1 | Anderlecht | |
FC København 2-3 APOEL FC *
| 26.08.2009 | APOEL FC | 3-1 | FC København | |
| 18.08.2009 | FC København | 1-0 | APOEL FC | |
Panathinaikos 2-5 Atlético Madrid *
| 25.08.2009 | Atlético Madrid | 2-0 | Panathinaikos | |
| 19.08.2009 | Panathinaikos | 2-3 | Atlético Madrid | |
Celtic FC 1-5 Arsenal FC *
| 26.08.2009 | Arsenal FC | 3-1 | Celtic FC | |
| 18.08.2009 | Celtic FC | 0-2 | Arsenal FC | |
FK Ventspils 1-5 FC Zürich *
| 25.08.2009 | FC Zürich | 2-1 | FK Ventspils | |
| 19.08.2009 | FK Ventspils | 0-3 | FC Zürich | |
Sporting Lisboa 3-3 Fiorentina *
| 26.08.2009 | Fiorentina | 1-1 | Sporting Lisboa | |
| 18.08.2009 | Sporting Lisboa | 2-2 | Fiorentina | |
Levski Sofia 1-4 Debrecen VSC *
| 25.08.2009 | Debrecen VSC | 2-0 | Levski Sofia | |
| 19.08.2009 | Levski Sofia | 1-2 | Debrecen VSC | |
RB Salzburg 1-5 Maccabi Haifa *
| 25.08.2009 | Maccabi Haifa | 3-0 | RB Salzburg | |
| 19.08.2009 | RB Salzburg | 1-2 | Maccabi Haifa | |
Sheriff Tiraspol 0-3 Olympiakos Pireus *
| 26.08.2009 | Olympiakos Pireus | 1-0 | Sheriff Tiraspol | |
| 18.08.2009 | Sheriff Tiraspol | 0-2 | Olympiakos Pireus | |
FC Timisoara 0-2 VfB Stuttgart *
| 26.08.2009 | VfB Stuttgart | 0-0 | FC Timisoara | |
| 18.08.2009 | FC Timisoara | 0-2 | VfB Stuttgart | |