*Slovan Bratislava 2-1 Dinamo Batumi
| 13.07.2022 | Dinamo Batumi | 1-2 AET | Slovan Bratislava | |
| 06.07.2022 | Slovan Bratislava | 0-0 | Dinamo Batumi | |
Tobol Kostanay 1-5 Ferencvaros TC *
| 13.07.2022 | Ferencvaros TC | 5-1 | Tobol Kostanay | |
| 06.07.2022 | Tobol Kostanay | 0-0 | Ferencvaros TC | |
*HJK Helsinki 2-2 FK RFS
| 12.07.2022 | FK RFS | 2-1/p.4-5 | HJK Helsinki | |
| 06.07.2022 | HJK Helsinki | 1-0 | FK RFS | |
*F91 Dudelange 3-1 KF Tirana
| 12.07.2022 | KF Tirana | 1-2 | F91 Dudelange | |
| 06.07.2022 | F91 Dudelange | 1-0 | KF Tirana | |
*FK Bodo/Glimt 4-3 KI Klaksvik
| 13.07.2022 | KI Klaksvik | 3-1 | FK Bodo/Glimt | |
| 06.07.2022 | FK Bodo/Glimt | 3-0 | KI Klaksvik | |
*Shkupi 3-2 Lincoln Red Imps
| 12.07.2022 | Lincoln Red Imps | 2-0 | Shkupi | |
| 05.07.2022 | Shkupi | 3-0 | Lincoln Red Imps | |
*Ludogorets 3-0 Sutjeska Niksic
| 12.07.2022 | Sutjeska Niksic | 0-1 | Ludogorets | |
| 05.07.2022 | Ludogorets | 2-0 | Sutjeska Niksic | |
*Maribor 2-0 Shakhter Soligorsk
| 13.07.2022 | Shakhter Soligorsk | 0-2 | Maribor | |
| 06.07.2022 | Maribor | 0-0 | Shakhter Soligorsk | |
Lech Poznan 2-5 Qarabag FK *
| 12.07.2022 | Qarabag FK | 5-1 | Lech Poznan | |
| 05.07.2022 | Lech Poznan | 1-0 | Qarabag FK | |
*Shamrock Rovers 3-0 Hibernians Paola
| 12.07.2022 | Hibernians Paola | 0-0 | Shamrock Rovers | |
| 05.07.2022 | Shamrock Rovers | 3-0 | Hibernians Paola | |
Zrinjski Mostar 0-1 Sheriff Tiraspol *
| 12.07.2022 | Sheriff Tiraspol | 1-0 | Zrinjski Mostar | |
| 06.07.2022 | Zrinjski Mostar | 0-0 | Sheriff Tiraspol | |
The New Saints 1-2 Linfield Belfast *
| 13.07.2022 | Linfield Belfast | 2-0 AET | The New Saints | |
| 05.07.2022 | The New Saints | 1-0 | Linfield Belfast | |
*Malmö FF 6-5 Vikingur Reykjavik
| 12.07.2022 | Vikingur Reykjavik | 3-3 | Malmö FF | |
| 05.07.2022 | Malmö FF | 3-2 | Vikingur Reykjavik | |
Ballkani 1-2 VMFD Zalgiris *
| 12.07.2022 | VMFD Zalgiris | 1-0 AET | Ballkani | |
| 05.07.2022 | Ballkani | 1-1 | VMFD Zalgiris | |