Dundee United 1-2 AEK Athens *
| 26.08.2010 | AEK Athens | 1-1 | Dundee United | |
| 19.08.2010 | Dundee United | 0-1 | AEK Athens | |
AIK Fotboll 1-2 Levski Sofia *
| 26.08.2010 | Levski Sofia | 2-1 | AIK Fotboll | |
| 19.08.2010 | AIK Fotboll | 0-0 | Levski Sofia | |
*CSKA Moscow 6-1 Anorthosis FC
| 24.08.2010 | Anorthosis FC | 1-2 | CSKA Moscow | |
| 19.08.2010 | CSKA Moscow | 4-0 | Anorthosis FC | |
*Aris Salonica 2-1 Austria Wien
| 26.08.2010 | Austria Wien | 1-1 | Aris Salonica | |
| 17.08.2010 | Aris Salonica | 1-0 | Austria Wien | |
*BATE Borisov 5-1 Marítimo
| 26.08.2010 | Marítimo | 1-2 | BATE Borisov | |
| 19.08.2010 | BATE Borisov | 3-0 | Marítimo | |
*Borussia Dortmund 5-0 Qarabag FK
| 26.08.2010 | Qarabag FK | 0-1 | Borussia Dortmund | |
| 19.08.2010 | Borussia Dortmund | 4-0 | Qarabag FK | |
*Sporting Lisboa 3-2 Brøndby IF
| 26.08.2010 | Brøndby IF | 0-3 | Sporting Lisboa | |
| 19.08.2010 | Sporting Lisboa | 0-2 | Brøndby IF | |
*CSKA Sofia 5-2 The New Saints
| 26.08.2010 | The New Saints | 2-2 | CSKA Sofia | |
| 19.08.2010 | CSKA Sofia | 3-0 | The New Saints | |
*Club Brugge 5-3 Dinamo Minsk
| 26.08.2010 | Dinamo Minsk | 2-3 | Club Brugge | |
| 19.08.2010 | Club Brugge | 2-1 | Dinamo Minsk | |
Racing Genk 2-7 FC Porto *
| 26.08.2010 | FC Porto | 4-2 | Racing Genk | |
| 19.08.2010 | Racing Genk | 0-3 | FC Porto | |
FC Timisoara 0-3 Manchester City *
| 26.08.2010 | Manchester City | 2-0 | FC Timisoara | |
| 19.08.2010 | FC Timisoara | 0-1 | Manchester City | |
Celtic FC 2-4 FC Utrecht *
| 26.08.2010 | FC Utrecht | 4-0 | Celtic FC | |
| 19.08.2010 | Celtic FC | 2-0 | FC Utrecht | |
*AZ Alkmaar 3-2 FK Aktobe
| 26.08.2010 | FK Aktobe | 2-1 | AZ Alkmaar | |
| 19.08.2010 | AZ Alkmaar | 2-0 | FK Aktobe | |
*Steaua Bucuresti 1-1 Grasshoppers
| 26.08.2010 | Grasshoppers | 1-0/p.3-4 | Steaua Bucuresti | |
| 19.08.2010 | Steaua Bucuresti | 1-0 | Grasshoppers | |
Gyori ETO FC 1-4 Dinamo Zagreb *
| 26.08.2010 | Dinamo Zagreb | 2-1 | Gyori ETO FC | |
| 19.08.2010 | Gyori ETO FC | 0-2 | Dinamo Zagreb | |
*Hajduk Split 5-2 Unirea Urziceni
| 26.08.2010 | Unirea Urziceni | 1-1 | Hajduk Split | |
| 19.08.2010 | Hajduk Split | 4-1 | Unirea Urziceni | |
*Besiktas JK 6-0 HJK Helsinki
| 26.08.2010 | HJK Helsinki | 0-4 | Besiktas JK | |
| 17.08.2010 | Besiktas JK | 2-0 | HJK Helsinki | |
Galatasaray SK 3-3 Karpaty Lviv* *
| 26.08.2010 | Karpaty Lviv* | 1-1 | Galatasaray SK | |
| 19.08.2010 | Galatasaray SK | 2-2 | Karpaty Lviv* | |
*Lausanne-Sport 2-2 Lokomotiv Moscow
| 26.08.2010 | Lokomotiv Moscow | 1-1/p.3-4 | Lausanne-Sport | |
| 19.08.2010 | Lausanne-Sport | 1-1 | Lokomotiv Moscow | |
Dnipro 0-1 Lech Poznan *
| 26.08.2010 | Lech Poznan | 0-0 | Dnipro | |
| 19.08.2010 | Dnipro | 0-1 | Lech Poznan | |
*Debrecen VSC 4-1 Litex Lovech
| 26.08.2010 | Litex Lovech | 1-2 | Debrecen VSC | |
| 19.08.2010 | Debrecen VSC | 2-0 | Litex Lovech | |
*Liverpool 3-1 Trabzonspor
| 26.08.2010 | Trabzonspor | 1-2 | Liverpool | |
| 19.08.2010 | Liverpool | 1-0 | Trabzonspor | |
*Paris St. Germain 5-4 Maccabi Tel Aviv
| 26.08.2010 | Maccabi Tel Aviv | 4-3 | Paris St. Germain | |
| 19.08.2010 | Paris St. Germain | 2-0 | Maccabi Tel Aviv | |
*Odense BK 3-1 Motherwell FC
| 26.08.2010 | Motherwell FC | 0-1 | Odense BK | |
| 19.08.2010 | Odense BK | 2-1 | Motherwell FC | |
Omonia Nicosia 2-3 Metalist Kharkiv *
| 26.08.2010 | Metalist Kharkiv | 2-2 | Omonia Nicosia | |
| 19.08.2010 | Omonia Nicosia | 0-1 | Metalist Kharkiv | |
*PAOK Salonica 2-1 Fenerbahçe SK
| 26.08.2010 | Fenerbahçe SK | 1-1 AET | PAOK Salonica | |
| 19.08.2010 | PAOK Salonica | 1-0 | Fenerbahçe SK | |
Sibir Novosibirsk* 1-5 PSV Eindhoven *
| 26.08.2010 | PSV Eindhoven | 5-0 | Sibir Novosibirsk* | |
| 19.08.2010 | Sibir Novosibirsk* | 1-0 | PSV Eindhoven | |
*Rapid Wien 4-3 Aston Villa
| 26.08.2010 | Aston Villa | 2-3 | Rapid Wien | |
| 19.08.2010 | Rapid Wien | 1-1 | Aston Villa | |
*SSC Napoli 3-0 IF Elfsborg
| 26.08.2010 | IF Elfsborg | 0-2 | SSC Napoli | |
| 19.08.2010 | SSC Napoli | 1-0 | IF Elfsborg | |
Sturm Graz 1-3 Juventus FC *
| 26.08.2010 | Juventus FC | 1-0 | Sturm Graz | |
| 19.08.2010 | Sturm Graz | 1-2 | Juventus FC | |
*Bayer Leverkusen 6-1 Tavriya Simferopol
| 26.08.2010 | Tavriya Simferopol | 1-3 | Bayer Leverkusen | |
| 19.08.2010 | Bayer Leverkusen | 3-0 | Tavriya Simferopol | |
Slovan Bratislava 2-3 VfB Stuttgart *
| 26.08.2010 | VfB Stuttgart | 2-2 | Slovan Bratislava | |
| 19.08.2010 | Slovan Bratislava | 0-1 | VfB Stuttgart | |
*Villarreal CF 7-1 Dnepr Mogilev
| 26.08.2010 | Dnepr Mogilev | 1-2 | Villarreal CF | |
| 19.08.2010 | Villarreal CF | 5-0 | Dnepr Mogilev | |