AJ Auxerre 2-2 Levski Sofia *
| 29.09.2005 | Levski Sofia | 1-0 | AJ Auxerre | |
| 15.09.2005 | AJ Auxerre | 2-1 | Levski Sofia | |
APOEL FC 1-4 Hertha BSC *
| 29.09.2005 | Hertha BSC | 3-1 | APOEL FC | |
| 15.09.2005 | APOEL FC | 0-1 | Hertha BSC | |
*AS Roma 5-1 Aris Salonica
| 29.09.2005 | Aris Salonica | 0-0 | AS Roma | |
| 15.09.2005 | AS Roma | 5-1 | Aris Salonica | |
Banik Ostrava 2-5 SC Heerenveen *
| 29.09.2005 | SC Heerenveen | 5-0 | Banik Ostrava | |
| 15.09.2005 | Banik Ostrava | 2-0 | SC Heerenveen | |
*Slavia Praha 4-1 Cork City
| 29.09.2005 | Cork City | 1-2 | Slavia Praha | |
| 15.09.2005 | Slavia Praha | 2-0 | Cork City | |
Bayer Leverkusen 0-2 CSKA Sofia *
| 29.09.2005 | CSKA Sofia | 1-0 | Bayer Leverkusen | |
| 15.09.2005 | Bayer Leverkusen | 0-1 | CSKA Sofia | |
*Shakhtar Donetsk 6-1 Debrecen VSC
| 29.09.2005 | Debrecen VSC | 0-2 | Shakhtar Donetsk | |
| 15.09.2005 | Shakhtar Donetsk | 4-1 | Debrecen VSC | |
Hibernian FC 1-5 Dnipro *
| 29.09.2005 | Dnipro | 5-1 | Hibernian FC | |
| 15.09.2005 | Hibernian FC | 0-0 | Dnipro | |
*VfB Stuttgart 2-1 Domžale
| 29.09.2005 | Domžale | 1-0 | VfB Stuttgart | |
| 15.09.2005 | VfB Stuttgart | 2-0 | Domžale | |
*Dinamo Bucuresti 5-2 Everton
| 29.09.2005 | Everton | 1-0 | Dinamo Bucuresti | |
| 15.09.2005 | Dinamo Bucuresti | 5-1 | Everton | |
*FC Basel 6-0 Siroki Brijeg
| 29.09.2005 | Siroki Brijeg | 0-1 | FC Basel | |
| 15.09.2005 | FC Basel | 5-0 | Siroki Brijeg | |
*Hamburger SV 2-1 FC København
| 29.09.2005 | FC København | 0-1 | Hamburger SV | |
| 15.09.2005 | Hamburger SV | 1-1 | FC København | |
*CSKA Moscow 6-2 FC Midtjylland
| 29.09.2005 | FC Midtjylland | 1-3 | CSKA Moscow | |
| 15.09.2005 | CSKA Moscow | 3-1 | FC Midtjylland | |
*Brøndby IF 3-2 FC Zürich
| 29.09.2005 | FC Zürich | 2-1 | Brøndby IF | |
| 15.09.2005 | Brøndby IF | 2-0 | FC Zürich | |
Feyenoord 1-2 Rapid Bucuresti *
| 29.09.2005 | Rapid Bucuresti | 1-0 | Feyenoord | |
| 15.09.2005 | Feyenoord | 1-1 | Rapid Bucuresti | |
*Tromso IL 2-1 Galatasaray SK
| 29.09.2005 | Galatasaray SK | 1-1 | Tromso IL | |
| 15.09.2005 | Tromso IL | 1-0 | Galatasaray SK | |
*Grasshoppers 4-1 MyPa
| 29.09.2005 | MyPa | 0-3 | Grasshoppers | |
| 15.09.2005 | Grasshoppers | 1-1 | MyPa | |
Grazer AK 0-7 Strasbourg *
| 29.09.2005 | Strasbourg | 5-0 | Grazer AK | |
| 15.09.2005 | Grazer AK | 0-2 | Strasbourg | |
*Halmstads BK 4-4 Sporting Lisboa
| 29.09.2005 | Sporting Lisboa | 2-3 AET | Halmstads BK | |
| 15.09.2005 | Halmstads BK | 1-2 | Sporting Lisboa | |
Krylia Sovetov Samara 6-6 AZ Alkmaar *
| 29.09.2005 | AZ Alkmaar | 3-1 | Krylia Sovetov Samara | |
| 15.09.2005 | Krylia Sovetov Samara | 5-3 | AZ Alkmaar | |
*Bolton Wanderers 4-2 Lokomotiv Plovdiv
| 29.09.2005 | Lokomotiv Plovdiv | 1-2 | Bolton Wanderers | |
| 15.09.2005 | Bolton Wanderers | 2-1 | Lokomotiv Plovdiv | |
*Maccabi Petah Tikva 5-4 FK Partizan
| 29.09.2005 | FK Partizan | 2-5 | Maccabi Petah Tikva | |
| 15.09.2005 | Maccabi Petah Tikva | 0-2 | FK Partizan | |
*Besiktas JK 4-2 Malmö FF
| 29.09.2005 | Malmö FF | 1-4 | Besiktas JK | |
| 15.09.2005 | Besiktas JK | 0-1 | Malmö FF | |
*Middlesbrough 2-0 SKODA Xanthi
| 29.09.2005 | SKODA Xanthi | 0-0 | Middlesbrough | |
| 15.09.2005 | Middlesbrough | 2-0 | SKODA Xanthi | |
Germinal Beerschot 0-0 Olympique Marseille *
| 29.09.2005 | Olympique Marseille | 0-0/p.4-1 | Germinal Beerschot | |
| 15.09.2005 | Germinal Beerschot | 0-0 | Olympique Marseille | |
*Palermo 6-1 Anorthosis FC
| 29.09.2005 | Anorthosis FC | 0-4 | Palermo | |
| 15.09.2005 | Palermo | 2-1 | Anorthosis FC | |
*PAOK Salonica 3-3 Metalurg Donetsk
| 29.09.2005 | Metalurg Donetsk | 2-2 | PAOK Salonica | |
| 15.09.2005 | PAOK Salonica | 1-1 | Metalurg Donetsk | |
*Litex Lovech 3-2 Racing Genk
| 29.09.2005 | Racing Genk | 0-1 | Litex Lovech | |
| 15.09.2005 | Litex Lovech | 2-2 | Racing Genk | |
Teplice 1-3 RCD Espanyol *
| 29.09.2005 | RCD Espanyol | 2-0 | Teplice | |
| 15.09.2005 | Teplice | 1-1 | RCD Espanyol | |
*FK Crvena Zvezda 1-1 SC Braga
| 29.09.2005 | SC Braga | 1-1 | FK Crvena Zvezda | |
| 15.09.2005 | FK Crvena Zvezda | 0-0 | SC Braga | |
*Sevilla FC 2-0 Mainz 05
| 29.09.2005 | Mainz 05 | 0-2 | Sevilla FC | |
| 15.09.2005 | Sevilla FC | 0-0 | Mainz 05 | |
SK Brann 3-5 Lokomotiv Moscow *
| 29.09.2005 | Lokomotiv Moscow | 3-2 | SK Brann | |
| 15.09.2005 | SK Brann | 1-2 | Lokomotiv Moscow | |
*Stade Rennais 3-1 CA Osasuna
| 29.09.2005 | CA Osasuna | 0-0 | Stade Rennais | |
| 15.09.2005 | Stade Rennais | 3-1 | CA Osasuna | |
Valerenga 1-6 Steaua Bucuresti *
| 29.09.2005 | Steaua Bucuresti | 3-1 | Valerenga | |
| 15.09.2005 | Valerenga | 0-3 | Steaua Bucuresti | |
*Viking FK 2-2 Austria Wien
| 29.09.2005 | Austria Wien | 2-1 | Viking FK | |
| 15.09.2005 | Viking FK | 1-0 | Austria Wien | |
Vitória Setúbal 1-2 Sampdoria *
| 29.09.2005 | Sampdoria | 1-0 | Vitória Setúbal | |
| 15.09.2005 | Vitória Setúbal | 1-1 | Sampdoria | |
*AS Monaco 5-1 Willem II Tilburg
| 29.09.2005 | Willem II Tilburg | 1-3 | AS Monaco | |
| 15.09.2005 | AS Monaco | 2-0 | Willem II Tilburg | |
*Vitória Guimarães 4-0 Wisła Kraków
| 29.09.2005 | Wisła Kraków | 0-1 | Vitória Guimarães | |
| 15.09.2005 | Vitória Guimarães | 3-0 | Wisła Kraków | |
*Zenit 1-0 AEK Athens
| 29.09.2005 | AEK Athens | 0-1 | Zenit | |
| 15.09.2005 | Zenit | 0-0 | AEK Athens | |