Dnipro 4-4 AC Bellinzona
| 28.08.2008 | AC Bellinzona | 2-1 | Dnipro | |
| 14.08.2008 | Dnipro | 3-2 | AC Bellinzona | |
APOEL FC 5-5 FK Crvena Zvezda
| 28.08.2008 | FK Crvena Zvezda | 3-3 AET | APOEL FC | |
| 14.08.2008 | APOEL FC | 2-2 | FK Crvena Zvezda | |
Aris Salonica 1-2 Slaven Belupo
| 28.08.2008 | Slaven Belupo | 2-0 | Aris Salonica | |
| 14.08.2008 | Aris Salonica | 1-0 | Slaven Belupo | |
Austria Wien 2-0 WIT Georgia
| 28.08.2008 | Austria Wien | 2-0 | WIT Georgia | |
Borac Cacak 2-1 Lokomotiv Sofia
| 26.08.2008 | Lokomotiv Sofia | 1-1 | Borac Cacak | |
| 14.08.2008 | Borac Cacak | 1-0 | Lokomotiv Sofia | |
FC Haka 0-6 Brøndby IF
| 28.08.2008 | Brøndby IF | 2-0 | FC Haka | |
| 14.08.2008 | FC Haka | 0-4 | Brøndby IF | |
BSC Young Boys 7-3 Debrecen VSC
| 28.08.2008 | Debrecen VSC | 2-3 | BSC Young Boys | |
| 14.08.2008 | BSC Young Boys | 4-1 | Debrecen VSC | |
Djurgårdens IF 2-6 Rosenborg BK
| 28.08.2008 | Rosenborg BK | 5-0 | Djurgårdens IF | |
| 14.08.2008 | Djurgårdens IF | 2-1 | Rosenborg BK | |
FC Honka Espoo 2-1 Viking FK
| 28.08.2008 | Viking FK | 1-2 | FC Honka Espoo | |
| 14.08.2008 | FC Honka Espoo | 0-0 | Viking FK | |
Manchester City 1-1 FC Midtjylland
| 28.08.2008 | FC Midtjylland | 0-1/p.2-4 | Manchester City | |
| 14.08.2008 | Manchester City | 0-1 | FC Midtjylland | |
Queen of the South 2-4 FC Nordsjælland
| 26.08.2008 | FC Nordsjælland | 2-1 | Queen of the South | |
| 14.08.2008 | Queen of the South | 1-2 | FC Nordsjælland | |
FC Zürich 2-2 Sturm Graz
| 28.08.2008 | Sturm Graz | 1-1/p.2-4 | FC Zürich | |
| 14.08.2008 | FC Zürich | 1-1 | Sturm Graz | |
FH Hafnarfjordur 2-5 Aston Villa
| 28.08.2008 | Aston Villa | 1-1 | FH Hafnarfjordur | |
| 14.08.2008 | FH Hafnarfjordur | 1-4 | Aston Villa | |
Legia Warszawa 1-4 FK Moscow
| 28.08.2008 | FK Moscow | 2-0 | Legia Warszawa | |
| 14.08.2008 | Legia Warszawa | 1-2 | FK Moscow | |
FK Vojvodina 0-3 Hapoel Tel Aviv
| 28.08.2008 | Hapoel Tel Aviv | 3-0 | FK Vojvodina | |
| 14.08.2008 | FK Vojvodina | 0-0 | Hapoel Tel Aviv | |
Deportivo La Coruña 2-0 Hajduk Split
| 28.08.2008 | Hajduk Split | 0-2 | Deportivo La Coruña | |
| 14.08.2008 | Deportivo La Coruña | 0-0 | Hajduk Split | |
Lech Poznan 6-0 Grasshoppers
| 28.08.2008 | Grasshoppers | 0-0 | Lech Poznan | |
| 14.08.2008 | Lech Poznan | 6-0 | Grasshoppers | |
FC København 7-3 Lillestrom SK
| 28.08.2008 | Lillestrom SK | 2-4 | FC København | |
| 14.08.2008 | FC København | 3-1 | Lillestrom SK | |
Litex Lovech 2-1 Ironi Kiryat Shmona
| 28.08.2008 | Ironi Kiryat Shmona | 1-2 | Litex Lovech | |
| 14.08.2008 | Litex Lovech | 0-0 | Ironi Kiryat Shmona | |
Maccabi Netanya 1-3 Cherno More Varna
| 28.08.2008 | Cherno More Varna | 2-0 | Maccabi Netanya | |
| 14.08.2008 | Maccabi Netanya | 1-1 | Cherno More Varna | |
Metalurgs Liepaja 1-5 SC Vaslui
| 28.08.2008 | SC Vaslui | 3-1 | Metalurgs Liepaja | |
| 14.08.2008 | Metalurgs Liepaja | 0-2 | SC Vaslui | |
Slovan Liberec 2-4 MSK Zilina
| 28.08.2008 | MSK Zilina | 2-1 | Slovan Liberec | |
| 14.08.2008 | Slovan Liberec | 1-2 | MSK Zilina | |
NK Interblock 0-3 Hertha BSC
| 28.08.2008 | Hertha BSC | 1-0 | NK Interblock | |
| 14.08.2008 | NK Interblock | 0-2 | Hertha BSC | |
AEK Athens 2-3 Omonia Nicosia
| 28.08.2008 | Omonia Nicosia | 2-2 | AEK Athens | |
| 14.08.2008 | AEK Athens | 0-1 | Omonia Nicosia | |
FK Suduva 2-4 RB Salzburg
| 28.08.2008 | RB Salzburg | 0-1 | FK Suduva | |
| 14.08.2008 | FK Suduva | 1-4 | RB Salzburg | |
SC Braga 3-0 Zrinjski Mostar
| 28.08.2008 | Zrinjski Mostar | 0-2 | SC Braga | |
| 14.08.2008 | SC Braga | 1-0 | Zrinjski Mostar | |
Siroki Brijeg 1-6 Besiktas JK
| 28.08.2008 | Besiktas JK | 4-0 | Siroki Brijeg | |
| 14.08.2008 | Siroki Brijeg | 1-2 | Besiktas JK | |
Vllaznia Shkodër 0-8 SSC Napoli
| 28.08.2008 | SSC Napoli | 5-0 | Vllaznia Shkodër | |
| 14.08.2008 | Vllaznia Shkodër | 0-3 | SSC Napoli | |
IF Elfsborg 3-4 St Patrick's Dublin
| 28.08.2008 | St Patrick's Dublin | 2-1 | IF Elfsborg | |
| 14.08.2008 | IF Elfsborg | 2-2 | St Patrick's Dublin | |
Stabaek 2-3 Stade Rennais
| 28.08.2008 | Stade Rennais | 2-0 | Stabaek | |
| 14.08.2008 | Stabaek | 2-1 | Stade Rennais | |
VfB Stuttgart 6-2 Gyori ETO FC
| 28.08.2008 | Gyori ETO FC | 1-4 | VfB Stuttgart | |
| 14.08.2008 | VfB Stuttgart | 2-1 | Gyori ETO FC | |