Ada Velipojë 2-5 KF Tirana *
| 08.12.2010 | KF Tirana | 2-2 | Ada Velipojë | |
| 24.11.2010 | Ada Velipojë | 0-3 | KF Tirana | |
KF Kamza 2-5 Dinamo Tirana *
| 08.12.2010 | Dinamo Tirana | 2-0 | KF Kamza | |
| 24.11.2010 | KF Kamza | 2-3 | Dinamo Tirana | |
*Bylis Ballsh 1-0 Flamurtari Vlore
| 08.12.2010 | Flamurtari Vlore | 0-1 | Bylis Ballsh | |
| 24.11.2010 | Bylis Ballsh | 0-0 | Flamurtari Vlore | |
Gramozi Ersekë 2-6 KF Laci *
| 08.12.2010 | KF Laci | 4-0 | Gramozi Ersekë | |
| 24.11.2010 | Gramozi Ersekë | 2-2 | KF Laci | |
KS Kastrioti 3-5 Shkumbini
| 08.12.2010 | Shkumbini | 2-2 | KS Kastrioti | |
| 25.11.2010 | KS Kastrioti | 1-3 | Shkumbini | |
KS Lushnja 0-1 Besa Kavaje *
| 08.12.2010 | Besa Kavaje | 1-0 | KS Lushnja | |
| 24.11.2010 | KS Lushnja | 0-0 | Besa Kavaje | |
*Skenderbeu 2-0 KF Teuta Durres
| 08.12.2010 | KF Teuta Durres | 0-2 | Skenderbeu | |
| 25.11.2010 | Skenderbeu | 0-0 | KF Teuta Durres | |
KS Elbasani 0-5 Vllaznia Shkodër *
| 08.12.2010 | Vllaznia Shkodër | 4-0 | KS Elbasani | |
| 24.11.2010 | KS Elbasani | 0-1 | Vllaznia Shkodër | |