*KSC Lokeren 4-4 KAA Gent
| 18.01.2012 | KAA Gent | 3-3 | KSC Lokeren | |
| 21.12.2011 | KSC Lokeren | 1-1 | KAA Gent | |
*KV Kortrijk 3-2 Beerschot AC*
| 18.01.2012 | Beerschot AC* | 2-1 | KV Kortrijk | |
| 21.12.2011 | KV Kortrijk | 2-0 | Beerschot AC* | |
*Lierse SK 5-4 Standard Liège
| 18.01.2012 | Standard Liège | 2-4 AET | Lierse SK | |
| 21.12.2011 | Lierse SK | 1-2 | Standard Liège | |
*RAEC Mons 5-3 Rupel Boom
| 18.01.2012 | Rupel Boom | 2-2 | RAEC Mons | |
| 21.12.2011 | RAEC Mons | 3-1 | Rupel Boom | |