Santa Cruz/PE 1-4 Atlético/GO *
| 23.04.2010 | Atlético/GO | 2-0 | Santa Cruz/PE | |
| 15.04.2010 | Santa Cruz/PE | 1-2 | Atlético/GO | |
*Palmeiras/SP 2-1 Atlético/PR
| 22.04.2010 | Atlético/PR | 1-1 | Palmeiras/SP | |
| 16.04.2010 | Palmeiras/SP | 1-0 | Atlético/PR | |
Corinthians/PR 1-3 Vasco da Gama/RJ *
| 21.04.2010 | Vasco da Gama/RJ | 2-1 | Corinthians/PR | |
| 15.04.2010 | Corinthians/PR | 0-1 | Vasco da Gama/RJ | |
*Vitória/BA 6-2 Goiás/GO
| 22.04.2010 | Goiás/GO | 2-2 | Vitória/BA | |
| 16.04.2010 | Vitória/BA | 4-0 | Goiás/GO | |
*Grêmio/RS 5-4 Avai FC/SC
| 22.04.2010 | Avai FC/SC | 3-2 | Grêmio/RS | |
| 15.04.2010 | Grêmio/RS | 3-1 | Avai FC/SC | |
Portuguesa/SP 2-4 Fluminense/RJ *
| 23.04.2010 | Fluminense/RJ | 3-2 | Portuguesa/SP | |
| 15.04.2010 | Portuguesa/SP | 0-1 | Fluminense/RJ | |
*Santos/SP 10-4 Guarani/SP
| 22.04.2010 | Guarani/SP | 3-2 | Santos/SP | |
| 15.04.2010 | Santos/SP | 8-1 | Guarani/SP | |
*Atlético Mineiro/MG 3-0 Sport Recife/PE
| 22.04.2010 | Sport Recife/PE | 0-2 | Atlético Mineiro/MG | |
| 15.04.2010 | Atlético Mineiro/MG | 1-0 | Sport Recife/PE | |