ABC Natal/RN 3-4 Vitória/BA *
| 19.04.2012 | Vitória/BA | 3-2 | ABC Natal/RN | |
| 12.04.2012 | ABC Natal/RN | 1-1 | Vitória/BA | |
Criciúma/SC 2-7 Atlético/PR *
| 13.04.2012 | Atlético/PR | 5-1 | Criciúma/SC | |
| 06.04.2012 | Criciúma/SC | 1-2 | Atlético/PR | |
Bahia de Feira/BA 2-5 São Paulo/SP *
| 12.04.2012 | Bahia de Feira/BA | 2-5 | São Paulo/SP | |
Guarani/SP 1-2 Botafogo/RJ *
| 19.04.2012 | Botafogo/RJ | 0-0 | Guarani/SP | |
| 05.04.2012 | Guarani/SP | 1-2 | Botafogo/RJ | |
Ceará SC/CE 3-3 Paraná/PR *
| 19.04.2012 | Paraná/PR | 1-1 | Ceará SC/CE | |
| 12.04.2012 | Ceará SC/CE | 2-2 | Paraná/PR | |
Chapecoense/SC 2-5 Cruzeiro/MG *
| 19.04.2012 | Cruzeiro/MG | 4-1 | Chapecoense/SC | |
| 12.04.2012 | Chapecoense/SC | 1-1 | Cruzeiro/MG | |
ASA/AL 1-3 Coritiba/PR *
| 12.04.2012 | Coritiba/PR | 3-0 | ASA/AL | |
| 05.04.2012 | ASA/AL | 1-0 | Coritiba/PR | |
América Mineiro/MG 3-4 Goiás/GO *
| 12.04.2012 | Goiás/GO | 4-3 | América Mineiro/MG | |
| 05.04.2012 | América Mineiro/MG | 0-0 | Goiás/GO | |
Ipatinga/MG 0-4 Grêmio/RS *
| 12.04.2012 | Grêmio/RS | 3-0 | Ipatinga/MG | |
| 05.04.2012 | Ipatinga/MG | 0-1 | Grêmio/RS | |
Horizonte/CE 1-3 Palmeiras/SP *
| 05.04.2012 | Horizonte/CE | 1-3 | Palmeiras/SP | |
*Fortaleza/CE 5-2 Nautico/PE
| 19.04.2012 | Nautico/PE | 2-1 | Fortaleza/CE | |
| 13.04.2012 | Fortaleza/CE | 4-0 | Nautico/PE | |
*Paysandu/PA 6-2 Sport Recife/PE
| 12.04.2012 | Sport Recife/PE | 1-4 | Paysandu/PA | |
| 05.04.2012 | Paysandu/PA | 2-1 | Sport Recife/PE | |
Penarol/AM 0-5 Atlético Mineiro/MG *
| 12.04.2012 | Penarol/AM | 0-5 | Atlético Mineiro/MG | |
Atlético/GO 3-3 Ponte Preta/SP *
| 19.04.2012 | Ponte Preta/SP | 2-1/p.4-3 | Atlético/GO | |
| 06.04.2012 | Atlético/GO | 2-1 | Ponte Preta/SP | |
Juventude/RS 2-4 Portuguesa/SP *
| 13.04.2012 | Portuguesa/SP | 4-0 | Juventude/RS | |
| 05.04.2012 | Juventude/RS | 2-0 | Portuguesa/SP | |