Atletico/AC 4-4 Santos Macapá/AP *
| 22.02.2018 | Santos Macapá/AP | 2-1 | Atletico/AC | |
| 01.02.2018 | Atletico/AC | 3-2 | Santos Macapá/AP | |
*CA Itapemirim/ES 5-3 Brasiliense/DF
| 15.02.2018 | Brasiliense/DF | 2-3 | CA Itapemirim/ES | |
| 31.01.2018 | CA Itapemirim/ES | 2-1 | Brasiliense/DF | |
Corumbaense/MS 2-5 Luverdense/MT *
| 22.02.2018 | Luverdense/MT | 3-2 | Corumbaense/MS | |
| 01.02.2018 | Corumbaense/MS | 0-2 | Luverdense/MT | |
Operario/MS 1-3 Cuiabá/MT *
| 16.02.2018 | Cuiabá/MT | 3-0 | Operario/MS | |
| 08.02.2018 | Operario/MS | 1-0 | Cuiabá/MT | |
Interporto FC/TO 0-4 Paysandu/PA
| 20.02.2018 | Paysandu/PA | 4-0 | Interporto FC/TO | |
| 10.02.2018 | Interporto FC/TO | 0-0 | Paysandu/PA | |
*Manaus FC/AM 3-1 Remo/PA
| 15.02.2018 | Remo/PA | 1-1 | Manaus FC/AM | |
| 01.02.2018 | Manaus FC/AM | 2-0 | Remo/PA | |
São Raimundo/RR 3-4 Rio Branco/AC *
| 22.02.2018 | Rio Branco/AC | 2-2 | São Raimundo/RR | |
| 01.02.2018 | São Raimundo/RR | 1-2 | Rio Branco/AC | |
*Sparta/TO 2-2 Real Ariquemes/RO
| 22.02.2018 | Real Ariquemes/RO | 1-1/p.2-4 | Sparta/TO | |
| 08.02.2018 | Sparta/TO | 1-1 | Real Ariquemes/RO | |