Figueirense/SC 2-2 Atlético Mineiro/MG *
| 15.03.2018 | Atlético Mineiro/MG | 1-2/p.4-2 | Figueirense/SC | |
| 01.03.2018 | Figueirense/SC | 0-1 | Atlético Mineiro/MG | |
*Atlético/PR 1-1 Ceará SC/CE
| 16.03.2018 | Ceará SC/CE | 1-1/p.5-6 | Atlético/PR | |
| 01.03.2018 | Atlético/PR | 0-0 | Ceará SC/CE | |
*São Paulo/SP 5-0 CRB/AL
| 14.03.2018 | CRB/AL | 0-3 | São Paulo/SP | |
| 28.02.2018 | São Paulo/SP | 2-0 | CRB/AL | |
*Nautico/PE 3-1 Cuiabá/MT
| 15.03.2018 | Cuiabá/MT | 0-1 | Nautico/PE | |
| 28.02.2018 | Nautico/PE | 2-1 | Cuiabá/MT | |
*Ferroviário/CE 2-1 Vila Nova/GO
| 16.03.2018 | Vila Nova/GO | 0-1 | Ferroviário/CE | |
| 01.03.2018 | Ferroviário/CE | 1-1 | Vila Nova/GO | |
Fluminense/RJ 1-3 Avai FC/SC *
| 16.03.2018 | Avai FC/SC | 1-0 | Fluminense/RJ | |
| 01.03.2018 | Fluminense/RJ | 1-2 | Avai FC/SC | |
*Goiás/GO 2-1 Coritiba/PR
| 14.03.2018 | Coritiba/PR | 1-1 | Goiás/GO | |
| 28.02.2018 | Goiás/GO | 1-0 | Coritiba/PR | |
*Internacional/RS 4-0 Cianorte/PR
| 14.03.2018 | Cianorte/PR | 0-2 | Internacional/RS | |
| 01.03.2018 | Internacional/RS | 2-0 | Cianorte/PR | |
*Ponte Preta/SP 0-0 Sampaio Correa/MA
| 15.03.2018 | Sampaio Correa/MA | 0-0/p.3-5 | Ponte Preta/SP | |
| 28.02.2018 | Ponte Preta/SP | 0-0 | Sampaio Correa/MA | |
Bragantino/SP 1-3 Vitória/BA *
| 15.03.2018 | Vitória/BA | 3-0 | Bragantino/SP | |
| 28.02.2018 | Bragantino/SP | 1-0 | Vitória/BA | |