Cascavel/PR 0-6 Maringá FC/PR *
| 20.03.2022 | Maringá FC/PR | 5-0 | Cascavel/PR | |
| 12.03.2022 | Cascavel/PR | 0-1 | Maringá FC/PR | |
Cianorte/PR 0-4 Coritiba/PR *
| 19.03.2022 | Coritiba/PR | 3-0 | Cianorte/PR | |
| 13.03.2022 | Cianorte/PR | 0-1 | Coritiba/PR | |
Ind. São-Joseense/PR 2-3 Operário F./PR *
| 19.03.2022 | Operário F./PR | 2-0 | Ind. São-Joseense/PR | |
| 13.03.2022 | Ind. São-Joseense/PR | 2-1 | Operário F./PR | |
Londrina/PR 2-2 Athletico/PR *
| 20.03.2022 | Athletico/PR | 2-1/p.4-2 | Londrina/PR | |
| 13.03.2022 | Londrina/PR | 1-0 | Athletico/PR | |