AE Paphos 1-3 Olympiakos Nicosia *
| 26.01.2011 | Olympiakos Nicosia | 3-1 | AE Paphos | |
| 12.01.2011 | AE Paphos | 0-0 | Olympiakos Nicosia | |
Doxa Katokopia 1-5 AEK Larnaca
| 19.01.2011 | AEK Larnaca | 4-1 | Doxa Katokopia | |
| 12.01.2011 | Doxa Katokopia | 0-1 | AEK Larnaca | |
AEL Limassol 0-1 Aris Limassol *
| 26.01.2011 | Aris Limassol | 0-0 | AEL Limassol | |
| 12.01.2011 | AEL Limassol | 0-1 | Aris Limassol | |
*Anorthosis FC 3-0 APEP FC
| 02.02.2011 | APEP FC | 0-1 | Anorthosis FC | |
| 12.01.2011 | Anorthosis FC | 2-0 | APEP FC | |
APOEL FC 1-3 Apollon Limassol *
| 19.01.2011 | Apollon Limassol | 2-0 | APOEL FC | |
| 12.01.2011 | APOEL FC | 1-1 | Apollon Limassol | |
*Omonia Nicosia 8-2 Atromitos Yeroskipou
| 26.01.2011 | Atromitos Yeroskipou | 2-2 | Omonia Nicosia | |
| 19.01.2011 | Omonia Nicosia | 6-0 | Atromitos Yeroskipou | |
EN Paralimni 3-5 Alki Larnaca *
| 16.02.2011 | Alki Larnaca | 4-3 | EN Paralimni | |
| 26.01.2011 | EN Paralimni | 0-1 | Alki Larnaca | |
Ermis Aradippou 1-2 Ethnikos Achnas *
| 19.01.2011 | Ethnikos Achnas | 1-1 | Ermis Aradippou | |
| 12.01.2011 | Ermis Aradippou | 0-1 | Ethnikos Achnas | |