*AEL Limassol 2-1 Nea Salamina
| 17.03.2021 | Nea Salamina | 1-0 | AEL Limassol | |
| 03.03.2021 | AEL Limassol | 2-0 | Nea Salamina | |
*APOEL FC 2-1 Omonia Nicosia
| 10.03.2021 | Omonia Nicosia | 0-1 | APOEL FC | |
| 24.02.2021 | APOEL FC | 1-1 | Omonia Nicosia | |
Ethnikos Achnas 1-2 Olympiakos Nicosia *
| 17.03.2021 | Olympiakos Nicosia | 1-0 | Ethnikos Achnas | |
| 03.03.2021 | Ethnikos Achnas | 1-1 | Olympiakos Nicosia | |
Karmiotissa Polemidion 2-7 Anorthosis FC *
| 10.03.2021 | Anorthosis FC | 5-1 | Karmiotissa Polemidion | |
| 24.02.2021 | Karmiotissa Polemidion | 1-2 | Anorthosis FC | |