AE Larisa 0-6 Asteras Tripoli *
| 13.01.2016 | Asteras Tripoli | 3-0 | AE Larisa | |
| 05.01.2016 | AE Larisa | 0-3 | Asteras Tripoli | |
AO Platanias 1-2 Atromitos FC *
| 12.01.2016 | Atromitos FC | 2-1 | AO Platanias | |
| 06.01.2016 | AO Platanias | 0-0 | Atromitos FC | |
Ergotelis Creta 0-2 Panionios GSS *
| 14.01.2016 | Panionios GSS | 1-0 | Ergotelis Creta | |
| 06.01.2016 | Ergotelis Creta | 0-1 | Panionios GSS | |
Levadiakos 0-3 AEK Athens *
| 13.01.2016 | AEK Athens | 2-0 | Levadiakos | |
| 06.01.2016 | Levadiakos | 0-1 | AEK Athens | |
AO Chania 1-10 Olympiakos Pireus *
| 13.01.2016 | Olympiakos Pireus | 6-0 | AO Chania | |
| 07.01.2016 | AO Chania | 1-4 | Olympiakos Pireus | |
AEL Kalloni 2-4 PAOK Salonica *
| 14.01.2016 | PAOK Salonica | 3-0 | AEL Kalloni | |
| 06.01.2016 | AEL Kalloni | 2-1 | PAOK Salonica | |
PAS Giannina 2-2 Panathinaikos *
| 14.01.2016 | Panathinaikos | 0-1 | PAS Giannina | |
| 07.01.2016 | PAS Giannina | 1-2 | Panathinaikos | |
Veria NFC 0-2 Iraklis Salonica *
| 13.01.2016 | Iraklis Salonica | 1-0 | Veria NFC | |
| 05.01.2016 | Veria NFC | 0-1 | Iraklis Salonica | |