*FC Astana 4-3 Caspiy Aktau
| 22.09.2021 | Caspiy Aktau | 0-1 AET | FC Astana | |
| 21.08.2021 | FC Astana | 3-3 | Caspiy Aktau | |
FK Kyzylzhar 0-2 Tobol Kostanay *
| 22.09.2021 | Tobol Kostanay | 1-0 | FK Kyzylzhar | |
| 21.08.2021 | FK Kyzylzhar | 0-1 | Tobol Kostanay | |
FK Taraz 1-3 Shakhtyor Karagandy *
| 27.10.2021 | Shakhtyor Karagandy | 3-1 | FK Taraz | |
| 22.09.2021 | FK Taraz | 0-0 | Shakhtyor Karagandy | |
*Kairat Almaty 5-0 Kaisar Kyzylorda
| 27.10.2021 | Kaisar Kyzylorda | 0-2 | Kairat Almaty | |
| 22.09.2021 | Kairat Almaty | 3-0 | Kaisar Kyzylorda | |