*Pelister Bitola 6-1 FK Babi
| 27.09.2012 | FK Babi | 1-1 | Pelister Bitola | |
| 09.09.2012 | Pelister Bitola | 5-0 | FK Babi | |
*Metalurg Skopje 4-3 FK Turnovo
| 26.09.2012 | FK Turnovo | 0-1 | Metalurg Skopje | |
| 09.09.2012 | Metalurg Skopje | 3-3 | FK Turnovo | |
Pobeda Prilep 0-2 Drita Bogovinje *
| 26.09.2012 | Drita Bogovinje | 2-0 | Pobeda Prilep | |
| 08.09.2012 | Pobeda Prilep | 0-0 | Drita Bogovinje | |
FK 11 Oktomvri 0-10 Renova *
| 26.09.2012 | Renova | 5-0 | FK 11 Oktomvri | |
| 09.09.2012 | FK 11 Oktomvri | 0-5 | Renova | |
*Shkendija'79 2-0 Bregalnica Stip
| 26.09.2012 | Bregalnica Stip | 0-1 | Shkendija'79 | |
| 09.09.2012 | Shkendija'79 | 1-0 | Bregalnica Stip | |
Bashkimi Kumanovo 0-4 Sileks Kratovo *
| 26.09.2012 | Sileks Kratovo | 3-0 | Bashkimi Kumanovo | |
| 09.09.2012 | Bashkimi Kumanovo | 0-1 | Sileks Kratovo | |
Lokomotiva Skopje 0-9 Teteks Tetovo *
| 26.09.2012 | Teteks Tetovo | 7-0 | Lokomotiva Skopje | |
| 09.09.2012 | Lokomotiva Skopje | 0-2 | Teteks Tetovo | |
*Vardar Skopje 4-1 FK Gorno Lisice
| 26.09.2012 | FK Gorno Lisice | 1-2 | Vardar Skopje | |
| 19.09.2012 | Vardar Skopje | 2-0 | FK Gorno Lisice | |