Atlético San Luis 0-2 Club Tijuana *
| 29.01.2020 | Club Tijuana | 1-0 | Atlético San Luis | |
| 22.01.2020 | Atlético San Luis | 0-1 | Club Tijuana | |
Cafetaleros Tapachula 4-4 Monarcas Morelia *
| 30.01.2020 | Monarcas Morelia | 3-0/p.3-2 | Cafetaleros Tapachula | |
| 23.01.2020 | Cafetaleros Tapachula | 4-1 | Monarcas Morelia | |
Celaya FC 3-7 CF Monterrey *
| 30.01.2020 | CF Monterrey | 3-0 | Celaya FC | |
| 23.01.2020 | Celaya FC | 3-4 | CF Monterrey | |
Club Atlas 4-4 Deportivo Toluca *
| 29.01.2020 | Deportivo Toluca | 3-2/p.5-3 | Club Atlas | |
| 23.01.2020 | Club Atlas | 2-1 | Deportivo Toluca | |
Querétaro FC 4-5 FC Juárez *
| 30.01.2020 | FC Juárez | 3-1 | Querétaro FC | |
| 22.01.2020 | Querétaro FC | 3-2 | FC Juárez | |
Guadalajara Chivas 2-2 Dorados Sinaloa *
| 29.01.2020 | Dorados Sinaloa | 0-1/p.6-5 | Guadalajara Chivas | |
| 22.01.2020 | Guadalajara Chivas | 1-2 | Dorados Sinaloa | |
*Santos Laguna 5-4 UNAM Pumas
| 30.01.2020 | UNAM Pumas | 2-1 | Santos Laguna | |
| 23.01.2020 | Santos Laguna | 4-2 | UNAM Pumas | |
Venados Yucatán 2-4 Pachuca CF *
| 29.01.2020 | Pachuca CF | 3-1 | Venados Yucatán | |
| 22.01.2020 | Venados Yucatán | 1-1 | Pachuca CF | |