*Albinegros Orizaba 2-0 Indios C. Juárez
| 21.11.2010 | Indios C. Juárez | 0-1 | Albinegros Orizaba | |
| 18.11.2010 | Albinegros Orizaba | 1-0 | Indios C. Juárez | |
*CD Irapuato 4-3 Alacranes Durango
| 21.11.2010 | Alacranes Durango | 3-2 | CD Irapuato | |
| 18.11.2010 | CD Irapuato | 2-0 | Alacranes Durango | |
*TR Veracruz 2-1 Lobos de la BUAP
| 22.11.2010 | Lobos de la BUAP | 0-1 | TR Veracruz | |
| 19.11.2010 | TR Veracruz | 1-1 | Lobos de la BUAP | |