Deportivo Toluca 1-0 Cruz Azul
| 05.12.2005 | Cruz Azul | 0-0 | Deportivo Toluca | |
| 01.12.2005 | Deportivo Toluca | 1-0 | Cruz Azul | |
Pachuca CF 4-0 Club Necaxa
| 04.12.2005 | Club Necaxa | 0-2 | Pachuca CF | |
| 01.12.2005 | Pachuca CF | 2-0 | Club Necaxa | |
Tigres UANL 5-4 Club América
| 05.12.2005 | Club América | 1-4 | Tigres UANL | |
| 02.12.2005 | Tigres UANL | 1-3 | Club América | |
UAG Tecos 0-7 CF Monterrey
| 04.12.2005 | CF Monterrey | 4-0 | UAG Tecos | |
| 01.12.2005 | UAG Tecos | 0-3 | CF Monterrey | |