Bokelj Kotor 0-4 FK Mogren *
| 03.11.2010 | FK Mogren | 1-0 | Bokelj Kotor | |
| 20.10.2010 | Bokelj Kotor | 0-3 | FK Mogren | |
*Rudar Pljevlja 4-1 Crvena Stijena
| 03.11.2010 | Crvena Stijena | 1-2 | Rudar Pljevlja | |
| 20.10.2010 | Rudar Pljevlja | 2-0 | Crvena Stijena | |
FK Gornja Zeta 0-10 FK Buducnost *
| 03.11.2010 | FK Buducnost | 6-0 | FK Gornja Zeta | |
| 20.10.2010 | FK Gornja Zeta | 0-4 | FK Buducnost | |
*OFK Petrovac 5-0 FK Jezero
| 03.11.2010 | FK Jezero | 0-2 | OFK Petrovac | |
| 20.10.2010 | OFK Petrovac | 3-0 | FK Jezero | |
FK Mladost 1-2 Decic Tuzi *
| 03.11.2010 | Decic Tuzi | 2-1 | FK Mladost | |
| 20.10.2010 | FK Mladost | 0-0 | Decic Tuzi | |
*FK Zeta 4-0 FK Pljevlja
| 03.11.2010 | FK Pljevlja | 0-3 | FK Zeta | |
| 20.10.2010 | FK Zeta | 1-0 | FK Pljevlja | |
Iskra Danilovgrad 1-4 Sutjeska Niksic *
| 03.11.2010 | Sutjeska Niksic | 2-0 | Iskra Danilovgrad | |
| 20.10.2010 | Iskra Danilovgrad | 1-2 | Sutjeska Niksic | |
*OFK Bar 2-1 Mornar Bar
| 03.11.2010 | Mornar Bar | 1-1 | OFK Bar | |
| 20.10.2010 | OFK Bar | 1-0 | Mornar Bar | |