Atlético Baleares 2-5 AE Prat *
| 14.12.2016 | AE Prat | 4-2 | Atlético Baleares | |
| 30.11.2016 | Atlético Baleares | 0-1 | AE Prat | |
*Burgos CF 3-2 Arandina CF
| 06.12.2016 | Arandina CF | 1-1 | Burgos CF | |
| 30.11.2016 | Burgos CF | 2-1 | Arandina CF | |
Atl. Mancha Real 1-6 CD Badajoz *
| 14.12.2016 | CD Badajoz | 4-0 | Atl. Mancha Real | |
| 30.11.2016 | Atl. Mancha Real | 1-2 | CD Badajoz | |
UD Poblense 3-3 CF Badalona *
| 14.12.2016 | CF Badalona | 1-1 | UD Poblense | |
| 30.11.2016 | UD Poblense | 2-2 | CF Badalona | |
CD Varea 1-5 Deportivo Alavés B *
| 13.12.2016 | Deportivo Alavés B | 2-0 | CD Varea | |
| 30.11.2016 | CD Varea | 1-3 | Deportivo Alavés B | |
Orihuela CF 1-3 Lorca Deportiva *
| 14.12.2016 | Lorca Deportiva | 2-0 | Orihuela CF | |
| 23.11.2016 | Orihuela CF | 1-1 | Lorca Deportiva | |
*SD Zamudio 3-2 Racing Santander B*
| 14.12.2016 | Racing Santander B* | 1-2 | SD Zamudio | |
| 30.11.2016 | SD Zamudio | 1-1 | Racing Santander B* | |
Peña Sport FC 0-1 Real Unión *
| 08.12.2016 | Real Unión | 0-0 | Peña Sport FC | |
| 30.11.2016 | Peña Sport FC | 0-1 | Real Unión | |
San Fernando CD 1-2 Linares Deportivo *
| 15.12.2016 | Linares Deportivo | 1-1 | San Fernando CD | |
| 01.12.2016 | San Fernando CD | 0-1 | Linares Deportivo | |
Arosa SC 1-9 SD Ponferradina *
| 14.12.2016 | SD Ponferradina | 4-0 | Arosa SC | |
| 30.11.2016 | Arosa SC | 1-5 | SD Ponferradina | |
*SD Tenisca 7-3 CD Madridejos
| 14.12.2016 | CD Madridejos | 2-0 | SD Tenisca | |
| 30.11.2016 | SD Tenisca | 7-1 | CD Madridejos | |
*Sporting Gijón B 3-0 Zamora CF
| 14.12.2016 | Zamora CF | 0-1 | Sporting Gijón B | |
| 30.11.2016 | Sporting Gijón B | 2-0 | Zamora CF | |
UB Conquense 2-2 CD Teruel *
| 14.12.2016 | CD Teruel | 0-1 | UB Conquense | |
| 30.11.2016 | UB Conquense | 1-2 | CD Teruel | |
*Atlético Saguntino 3-0 UCAM Murcia B
| 14.12.2016 | UCAM Murcia B | 0-1 | Atlético Saguntino | |
| 01.12.2016 | Atlético Saguntino | 2-0 | UCAM Murcia B | |
*CF Fuenlabrada 2-2 UD S.S. Reyes
| 14.12.2016 | UD S.S. Reyes | 2-1 | CF Fuenlabrada | |
| 30.11.2016 | CF Fuenlabrada | 1-0 | UD S.S. Reyes | |
Andorra CF 2-12 UD Socuéllamos *
| 14.12.2016 | UD Socuéllamos | 8-2 | Andorra CF | |
| 30.11.2016 | Andorra CF | 0-4 | UD Socuéllamos | |