*Athletic Bilbao 2-2 RCD Espanyol
| 16.01.2008 | RCD Espanyol | 1-1/p.3-4 | Athletic Bilbao | |
| 09.01.2008 | Athletic Bilbao | 1-1 | RCD Espanyol | |
Sevilla FC 1-1 FC Barcelona *
| 15.01.2008 | FC Barcelona | 0-0 | Sevilla FC | |
| 09.01.2008 | Sevilla FC | 1-1 | FC Barcelona | |
Getafe CF 4-0 Levante UD
| 16.01.2008 | Levante UD | 0-1 | Getafe CF | |
| 09.01.2008 | Getafe CF | 3-0 | Levante UD | |
Real Mallorca 3-1 Real Madrid
| 16.01.2008 | Real Madrid | 0-1 | Real Mallorca | |
| 10.01.2008 | Real Mallorca | 2-1 | Real Madrid | |
Atlético Madrid 1-1 Real Valladolid
| 16.01.2008 | Real Valladolid | 1-1 | Atlético Madrid | |
| 10.01.2008 | Atlético Madrid | 0-0 | Real Valladolid | |
Real Zaragoza 3-5 Racing Santander
| 16.01.2008 | Racing Santander | 4-2 | Real Zaragoza | |
| 09.01.2008 | Real Zaragoza | 1-1 | Racing Santander | |
Real Betis 2-4 Valencia CF
| 16.01.2008 | Valencia CF | 2-1 | Real Betis | |
| 09.01.2008 | Real Betis | 1-2 | Valencia CF | |
Recreativo Huelva 1-2 Villarreal CF
| 16.01.2008 | Villarreal CF | 2-0 AET | Recreativo Huelva | |
| 09.01.2008 | Recreativo Huelva | 1-0 | Villarreal CF | |