DC United 0-2 New York Red Bulls *
| 08.11.2015 | New York Red Bulls | 1-0 | DC United | |
| 01.11.2015 | DC United | 0-1 | New York Red Bulls | |
Montreal Impact 3-4 Columbus Crew *
| 08.11.2015 | Columbus Crew | 3-1 AET | Montreal Impact | |
| 02.11.2015 | Montreal Impact | 2-1 | Columbus Crew | |
*Portland Timbers 2-0 Vancouver WC
| 09.11.2015 | Vancouver WC | 0-2 | Portland Timbers | |
| 01.11.2015 | Portland Timbers | 0-0 | Vancouver WC | |
Seattle Sounders 3-3 FC Dallas *
| 09.11.2015 | FC Dallas | 2-1/p.4-2 | Seattle Sounders | |
| 02.11.2015 | Seattle Sounders | 2-1 | FC Dallas | |