Los Angeles Galaxy 1-1 Colorado Rapids *
| 06.11.2016 | Colorado Rapids | 1-0/p.3-1 | Los Angeles Galaxy | |
| 30.10.2016 | Los Angeles Galaxy | 1-0 | Colorado Rapids | |
*Montreal Impact 3-1 New York Red Bulls
| 06.11.2016 | New York Red Bulls | 1-2 | Montreal Impact | |
| 30.10.2016 | Montreal Impact | 1-0 | New York Red Bulls | |
*Seattle Sounders 4-2 FC Dallas
| 07.11.2016 | FC Dallas | 2-1 | Seattle Sounders | |
| 31.10.2016 | Seattle Sounders | 3-0 | FC Dallas | |
*Toronto FC 7-0 New York City FC
| 07.11.2016 | New York City FC | 0-5 | Toronto FC | |
| 31.10.2016 | Toronto FC | 2-0 | New York City FC | |