Rochester Rhinos 2-1 Charleston Battery
| 29.09.2008 | Charleston Battery | 1-0 | Rochester Rhinos | |
| 27.09.2008 | Rochester Rhinos | 2-0 | Charleston Battery | |
Seattle Sounders 3-4 Montreal Impact
| 28.09.2008 | Montreal Impact | 3-1 | Seattle Sounders | |
| 27.09.2008 | Seattle Sounders | 2-1 | Montreal Impact | |
Vancouver WC 5-4 Minnesota Thunder
| 29.09.2008 | Minnesota Thunder | 4-3 | Vancouver WC | |
| 27.09.2008 | Vancouver WC | 2-0 | Minnesota Thunder | |