*Algeria (W) 14-0 Sudan (W)
| 26.10.2021 | Sudan (W) | CANC | Algeria (W) | |
| 20.10.2021 | Algeria (W) | 14-0 | Sudan (W) | |
Angola (W) 1-7 Botswana (W) *
| 26.10.2021 | Botswana (W) | 2-0 | Angola (W) | |
| 20.10.2021 | Angola (W) | 1-5 | Botswana (W) | |
*Burkina Faso (W) 5-2 Benin (W)
| 24.10.2021 | Benin (W) | 1-3 | Burkina Faso (W) | |
| 20.10.2021 | Burkina Faso (W) | 2-1 | Benin (W) | |
Central A. R. (W) 0-3 Cameroon (W) *
| 24.10.2021 | Cameroon (W) | 2-0 | Central A. R. (W) | |
| 20.10.2021 | Central A. R. (W) | 0-1 | Cameroon (W) | |
*Djibouti (W) 6-0 Rwanda (W)
| 26.10.2021 | Rwanda (W) | 0-3 W.O. | Djibouti (W) | |
| 20.10.2021 | Djibouti (W) | 3-0 W.O. | Rwanda (W) | |
Egypt (W) 2-7 Tunisia (W) *
| 26.10.2021 | Tunisia (W) | 1-0 | Egypt (W) | |
| 20.10.2021 | Egypt (W) | 2-6 | Tunisia (W) | |
*Equatorial Guinea (W) 6-0 DR Congo (W)
| 24.10.2021 | DR Congo (W) | 0-3 W.O. | Equatorial Guinea (W) | |
| 20.10.2021 | Equatorial Guinea (W) | 3-0 W.O. | DR Congo (W) | |
Eritrea (W) 0-6 Burundi (W) *
| 26.10.2021 | Burundi (W) | 1-0 | Eritrea (W) | |
| 20.10.2021 | Eritrea (W) | 0-5 | Burundi (W) | |
*Zimbabwe (W) 6-1 Eswatini (W)
| 26.10.2021 | Eswatini (W) | 0-3 | Zimbabwe (W) | |
| 20.10.2021 | Zimbabwe (W) | 3-1 | Eswatini (W) | |
Sierra Leone (W) 1-3 Gambia (W) *
| 25.10.2021 | Gambia (W) | 1-1 | Sierra Leone (W) | |
| 18.10.2021 | Sierra Leone (W) | 0-2 | Gambia (W) | |
*Nigeria (W) 2-1 Ghana (W)
| 24.10.2021 | Ghana (W) | 1-0 | Nigeria (W) | |
| 20.10.2021 | Nigeria (W) | 2-0 | Ghana (W) | |
*Guinea-Bissau (W) 2-0 Mauritania (W)
| 26.10.2021 | Mauritania (W) | 0-1 | Guinea-Bissau (W) | |
| 20.10.2021 | Guinea-Bissau (W) | 1-0 | Mauritania (W) | |
Niger (W) 0-20 Ivory Coast (W) *
| 25.10.2021 | Ivory Coast (W) | 11-0 | Niger (W) | |
| 20.10.2021 | Niger (W) | 0-9 | Ivory Coast (W) | |
*Kenya (W) 15-1 South Sudan (W)
| 23.10.2021 | South Sudan (W) | 1-7 | Kenya (W) | |
| 20.10.2021 | Kenya (W) | 8-0 | South Sudan (W) | |
Malawi (W) 3-4 Zambia (W) *
| 26.10.2021 | Zambia (W) | 3-2 | Malawi (W) | |
| 20.10.2021 | Malawi (W) | 1-1 | Zambia (W) | |
*Mali (W) 4-2 Guinea (W)
| 25.10.2021 | Guinea (W) | 0-2 | Mali (W) | |
| 20.10.2021 | Mali (W) | 2-2 | Guinea (W) | |
Tanzania (W) 3-5 Namibia (W) *
| 23.10.2021 | Namibia (W) | 3-2 | Tanzania (W) | |
| 20.10.2021 | Tanzania (W) | 1-2 | Namibia (W) | |
São Tomé & P. (W) 0-8 Togo (W) *
| 26.10.2021 | Togo (W) | 3-0 W.O. | São Tomé & P. (W) | |
| 22.10.2021 | São Tomé & P. (W) | 0-5 | Togo (W) | |
Liberia (W) 1-8 Senegal (W) *
| 26.10.2021 | Senegal (W) | 6-0 | Liberia (W) | |
| 20.10.2021 | Liberia (W) | 1-2 | Senegal (W) | |
Mozambique (W) 0-13 South Africa (W) *
| 26.10.2021 | South Africa (W) | 6-0 | Mozambique (W) | |
| 20.10.2021 | Mozambique (W) | 0-7 | South Africa (W) | |
*Uganda (W) 2-2 Ethiopia (W)
| 26.10.2021 | Ethiopia (W) | 2-0/p.1-2 | Uganda (W) | |
| 20.10.2021 | Uganda (W) | 2-0 | Ethiopia (W) | |