*Ahly Cairo 4-3 Esperance ST
| 23.09.2017 | Esperance ST | 1-2 | Ahly Cairo | |
| 16.09.2017 | Ahly Cairo | 2-2 | Esperance ST | |
Al Ahli Tripoli 0-2 Étoile Sahel Sousse *
| 24.09.2017 | Étoile Sahel Sousse | 2-0 | Al Ahli Tripoli | |
| 17.09.2017 | Al Ahli Tripoli | 0-0 | Étoile Sahel Sousse | |
Ferroviário da Beira 1-1 USM Alger *
| 23.09.2017 | USM Alger | 0-0 | Ferroviário da Beira | |
| 16.09.2017 | Ferroviário da Beira | 1-1 | USM Alger | |
Mamelodi Sundowns 1-1 Wydad Casablanca *
| 23.09.2017 | Wydad Casablanca | 1-0/p.3-2 | Mamelodi Sundowns | |
| 17.09.2017 | Mamelodi Sundowns | 1-0 | Wydad Casablanca | |