CS Constantine 3-6 Esperance ST *
| 13.04.2019 | Esperance ST | 3-1 | CS Constantine | |
| 06.04.2019 | CS Constantine | 2-3 | Esperance ST | |
Horoya AC 0-5 Wydad Casablanca *
| 13.04.2019 | Wydad Casablanca | 5-0 | Horoya AC | |
| 06.04.2019 | Horoya AC | 0-0 | Wydad Casablanca | |
*Mamelodi Sundowns 5-1 Al Ahly Cairo
| 13.04.2019 | Al Ahly Cairo | 1-0 | Mamelodi Sundowns | |
| 06.04.2019 | Mamelodi Sundowns | 5-0 | Al Ahly Cairo | |
Simba SC 1-4 TP Mazembe *
| 13.04.2019 | TP Mazembe | 4-1 | Simba SC | |
| 06.04.2019 | Simba SC | 0-0 | TP Mazembe | |