KMKM 0-4 1º de Agosto *
| 24.08.2019 | 1º de Agosto | 2-0 | KMKM | |
| 10.08.2019 | KMKM | 0-2 | 1º de Agosto | |
Aigle Noir 1-5 Gor Mahia *
| 25.08.2019 | Gor Mahia | 5-1 | Aigle Noir | |
| 11.08.2019 | Aigle Noir | 0-0 | Gor Mahia | |
Atlabara Juba 0-13 Al Ahly Cairo *
| 23.08.2019 | Al Ahly Cairo | 9-0 | Atlabara Juba | |
| 11.08.2019 | Atlabara Juba | 0-4 | Al Ahly Cairo | |
*JS Kabylie 3-3 Al Merreikh SC
| 24.08.2019 | Al Merreikh SC | 3-2 | JS Kabylie | |
| 09.08.2019 | JS Kabylie | 1-0 | Al Merreikh SC | |
AS Tempête Mocaf 2-3 Nasr Benghazi *
| 25.08.2019 | Nasr Benghazi | 3-1 | AS Tempête Mocaf | |
| 11.08.2019 | AS Tempête Mocaf | 1-0 | Nasr Benghazi | |
UMS de Loum 0-1 AS Vita Club *
| 25.08.2019 | AS Vita Club | 1-0 | UMS de Loum | |
| 11.08.2019 | UMS de Loum | 0-0 | AS Vita Club | |
Buffles du Borgou 1-2 ASC Kara *
| 25.08.2019 | ASC Kara | 1-0 | Buffles du Borgou | |
| 11.08.2019 | Buffles du Borgou | 1-1 | ASC Kara | |
Brikama United 3-7 Raja Casablanca *
| 24.08.2019 | Raja Casablanca | 4-0 | Brikama United | |
| 10.08.2019 | Brikama United | 3-3 | Raja Casablanca | |
*Cano Sport 3-2 Mekelle 70
| 25.08.2019 | Mekelle 70 | 1-1 | Cano Sport | |
| 10.08.2019 | Cano Sport | 2-1 | Mekelle 70 | |
Cercle Mbéri Sportif 0-2 Elect Sport FC *
| 25.08.2019 | Elect Sport FC | 2-0 | Cercle Mbéri Sportif | |
| 11.08.2019 | Cercle Mbéri Sportif | 0-0 | Elect Sport FC | |
Dekedaha FC 0-13 Zamalek SC *
| 24.08.2019 | Zamalek SC | 6-0 | Dekedaha FC | |
| 16.08.2019 | Dekedaha FC | 0-7 | Zamalek SC | |
Hafia FC 3-8 Étoile Sahel Sousse *
| 24.08.2019 | Étoile Sahel Sousse | 7-1 | Hafia FC | |
| 11.08.2019 | Hafia FC | 2-1 | Étoile Sahel Sousse | |
SO Armée 0-1 FC Nouadhibou *
| 25.08.2019 | FC Nouadhibou | 1-0 | SO Armée | |
| 11.08.2019 | SO Armée | 0-0 | FC Nouadhibou | |
Nyasa Big Bullets 2-3 FC Platinum (ZIM) *
| 24.08.2019 | FC Platinum (ZIM) | 3-2 | Nyasa Big Bullets | |
| 10.08.2019 | Nyasa Big Bullets | 0-0 | FC Platinum (ZIM) | |
Fomboni FC 3-3 Côte d'Or FC *
| 23.08.2019 | Côte d'Or FC | 1-1 | Fomboni FC | |
| 11.08.2019 | Fomboni FC | 2-2 | Côte d'Or FC | |
*Fosa Juniors 2-1 Pamplemousses
| 25.08.2019 | Pamplemousses | 1-1 | Fosa Juniors | |
| 10.08.2019 | Fosa Juniors | 1-0 | Pamplemousses | |
Stade Malien 1-2 Horoya AC *
| 25.08.2019 | Horoya AC | 1-0 | Stade Malien | |
| 10.08.2019 | Stade Malien | 1-1 | Horoya AC | |
Kano Pillars 3-4 Asante Kotoko *
| 25.08.2019 | Asante Kotoko | 2-0 | Kano Pillars | |
| 10.08.2019 | Kano Pillars | 3-2 | Asante Kotoko | |
African Stars FC 3-4 KCCA FC *
| 23.08.2019 | KCCA FC | 2-0 | African Stars FC | |
| 10.08.2019 | African Stars FC | 3-2 | KCCA FC | |
LPRC Oilers 1-3 AS Génération Foot *
| 24.08.2019 | AS Génération Foot | 3-0 | LPRC Oilers | |
| 11.08.2019 | LPRC Oilers | 1-0 | AS Génération Foot | |
AS Otôho 2-5 Mamelodi Sundowns *
| 24.08.2019 | Mamelodi Sundowns | 4-0 | AS Otôho | |
| 11.08.2019 | AS Otôho | 2-1 | Mamelodi Sundowns | |
Matlama FC 0-4 Petro Atlético Luanda *
| 25.08.2019 | Petro Atlético Luanda | 2-0 | Matlama FC | |
| 11.08.2019 | Matlama FC | 0-2 | Petro Atlético Luanda | |
*Green Eagles 2-1 Orlando Pirates
| 24.08.2019 | Orlando Pirates | 1-1 | Green Eagles | |
| 10.08.2019 | Green Eagles | 1-0 | Orlando Pirates | |
Rahimo FC 1-5 Enyimba FC *
| 25.08.2019 | Enyimba FC | 5-0 | Rahimo FC | |
| 10.08.2019 | Rahimo FC | 1-0 | Enyimba FC | |
Rayon Sports 1-1 Al Hilal Al Sudani *
| 25.08.2019 | Al Hilal Al Sudani | 0-0 | Rayon Sports | |
| 11.08.2019 | Rayon Sports | 1-1 | Al Hilal Al Sudani | |
*Young Africans 2-1 Township Rollers
| 24.08.2019 | Township Rollers | 0-1 | Young Africans | |
| 10.08.2019 | Young Africans | 1-1 | Township Rollers | |
AS SONIDEB 2-5 USM Alger *
| 25.08.2019 | USM Alger | 3-1 | AS SONIDEB | |
| 09.08.2019 | AS SONIDEB | 1-2 | USM Alger | |
Green Mamba 0-3 ZESCO United *
| 24.08.2019 | ZESCO United | 1-0 | Green Mamba | |
| 10.08.2019 | Green Mamba | 0-2 | ZESCO United | |