*US Ben Guerdane 5-1 Amarat United
| 25.08.2019 | Amarat United | 0-0 | US Ben Guerdane | |
| 11.08.2019 | US Ben Guerdane | 5-1 | Amarat United | |
AS Arta 1-4 Khartoum Al Watani *
| 23.08.2019 | Khartoum Al Watani | 3-0 | AS Arta | |
| 11.08.2019 | AS Arta | 1-1 | Khartoum Al Watani | |
*AS Pélican 2-2 AS Maniema Union
| 25.08.2019 | AS Maniema Union | 1-1/p.2-4 | AS Pélican | |
| 10.08.2019 | AS Pélican | 1-1 | AS Maniema Union | |
Akonangui 1-4 Ashanti Gold SC *
| 24.08.2019 | Ashanti Gold SC | 3-0 | Akonangui | |
| 10.08.2019 | Akonangui | 1-1 | Ashanti Gold SC | |
Fasil Kenema 2-3 Azam FC *
| 24.08.2019 | Azam FC | 3-1 | Fasil Kenema | |
| 11.08.2019 | Fasil Kenema | 1-0 | Azam FC | |
*Bandari FC 1-1 Ahli Shandi
| 23.08.2019 | Ahli Shandi | 1-1 | Bandari FC | |
| 10.08.2019 | Bandari FC | 0-0 | Ahli Shandi | |
*Bolton City YC (MRI) 3-2 Jwaneng Galaxy
| 25.08.2019 | Jwaneng Galaxy | 1-0 | Bolton City YC (MRI) | |
| 11.08.2019 | Bolton City YC (MRI) | 3-1 | Jwaneng Galaxy | |
Buildcon Ndola 1-2 Young Buffaloes *
| 24.08.2019 | Young Buffaloes | 1-1 | Buildcon Ndola | |
| 10.08.2019 | Buildcon Ndola | 0-1 | Young Buffaloes | |
*Paradou AC 3-1 CI Kamsar
| 24.08.2019 | CI Kamsar | 1-0 | Paradou AC | |
| 09.08.2019 | Paradou AC | 3-0 | CI Kamsar | |
*CR Belouizdad 4-0 AS CotonTchad
| 24.08.2019 | AS CotonTchad | 0-2 | CR Belouizdad | |
| 10.08.2019 | CR Belouizdad | 2-0 | AS CotonTchad | |
*DC Motema Pembe 4-0 Stade Renard
| 25.08.2019 | Stade Renard | 0-2 | DC Motema Pembe | |
| 12.08.2019 | DC Motema Pembe | 2-0 | Stade Renard | |
US GN 1-3 Ittihad Tripoli *
| 25.08.2019 | Ittihad Tripoli | 2-0 | US GN | |
| 11.08.2019 | US GN | 1-1 | Ittihad Tripoli | |
*Maranatha FC 3-0 LISCR Monrovia
| 25.08.2019 | LISCR Monrovia | 0-0 | Maranatha FC | |
| 11.08.2019 | Maranatha FC | 3-0 | LISCR Monrovia | |
Mogadishu City 0-1 Malindi SC *
| 24.08.2019 | Malindi SC | 1-0 | Mogadishu City | |
| 11.08.2019 | Mogadishu City | 0-0 | Malindi SC | |
*Proline FC 3-0 Masters Security
| 24.08.2019 | Masters Security | 0-0 | Proline FC | |
| 10.08.2019 | Proline FC | 3-0 | Masters Security | |
Niger Tornadoes 4-5 Santoba FC *
| 23.08.2019 | Santoba FC | 3-3 | Niger Tornadoes | |
| 10.08.2019 | Niger Tornadoes | 1-2 | Santoba FC | |
*Pyramids FC 5-1 Étoile du Congo
| 25.08.2019 | Étoile du Congo | 0-1 | Pyramids FC | |
| 10.08.2019 | Pyramids FC | 4-1 | Étoile du Congo | |
*Triangle United FC 5-0 Rukinzo FC
| 24.08.2019 | Rukinzo FC | 0-0 | Triangle United FC | |
| 11.08.2019 | Triangle United FC | 5-0 | Rukinzo FC | |
*TS Galaxy FC 2-0 St Louis Suns United
| 25.08.2019 | St Louis Suns United | 0-1 | TS Galaxy FC | |
| 11.08.2019 | TS Galaxy FC | 1-0 | St Louis Suns United | |