*CS Herediano 10-2 Alpha United
| 05.08.2011 | Alpha United | 2-2 | CS Herediano | |
| 27.07.2011 | CS Herediano | 8-0 | Alpha United | |
*CD Motagua 4-2 CSD Municipal
| 05.08.2011 | CSD Municipal | 2-0 | CD Motagua | |
| 29.07.2011 | CD Motagua | 4-0 | CSD Municipal | |
Alianza FC (SLV) 0-2 FC Dallas *
| 04.08.2011 | FC Dallas | 1-0 | Alianza FC (SLV) | |
| 29.07.2011 | Alianza FC (SLV) | 0-1 | FC Dallas | |
*Monarcas Morelia 7-0 Tempête FC
| 04.08.2011 | Tempête FC | 0-2 | Monarcas Morelia | |
| 29.07.2011 | Monarcas Morelia | 5-0 | Tempête FC | |
*Isidro Metapán 3-3 Puerto Rico Islanders
| 04.08.2011 | Puerto Rico Islanders | 3-1 | Isidro Metapán | |
| 28.07.2011 | Isidro Metapán | 2-0 | Puerto Rico Islanders | |
*Santos Laguna 4-3 CD Olimpia
| 04.08.2011 | CD Olimpia | 2-1 | Santos Laguna | |
| 28.07.2011 | Santos Laguna | 3-1 | CD Olimpia | |
San Francisco FC 1-2 Seattle Sounders *
| 04.08.2011 | Seattle Sounders | 2-0 AET | San Francisco FC | |
| 27.07.2011 | San Francisco FC | 1-0 | Seattle Sounders | |
*Toronto FC 4-2 Real Estelí
| 03.08.2011 | Real Estelí | 1-2 | Toronto FC | |
| 28.07.2011 | Toronto FC | 2-1 | Real Estelí | |