*Atlético/PR 3-3 Cerro Porteño
| 26.05.2005 | Cerro Porteño | 2-1/p.4-5 | Atlético/PR | |
| 19.05.2005 | Atlético/PR | 2-1 | Cerro Porteño | |
Junior Barranquilla 3-7 Boca Juniors *
| 26.05.2005 | Boca Juniors | 4-0 | Junior Barranquilla | |
| 17.05.2005 | Junior Barranquilla | 3-3 | Boca Juniors | |
*CA Banfield 5-0 Independiente Medellín
| 24.05.2005 | Independiente Medellín | 0-2 | CA Banfield | |
| 18.05.2005 | CA Banfield | 3-0 | Independiente Medellín | |
Pachuca CF 2-4 Guadalajara Chivas *
| 24.05.2005 | Guadalajara Chivas | 3-1 | Pachuca CF | |
| 18.05.2005 | Pachuca CF | 1-1 | Guadalajara Chivas | |
Palmeiras/SP 0-3 São Paulo/SP *
| 25.05.2005 | São Paulo/SP | 2-0 | Palmeiras/SP | |
| 18.05.2005 | Palmeiras/SP | 0-1 | São Paulo/SP | |
LDU Quito 4-5 River Plate *
| 26.05.2005 | River Plate | 4-2 | LDU Quito | |
| 17.05.2005 | LDU Quito | 2-1 | River Plate | |
Univ de Chile 2-4 Santos/SP *
| 25.05.2005 | Santos/SP | 3-0 | Univ de Chile | |
| 19.05.2005 | Univ de Chile | 2-1 | Santos/SP | |
Once Caldas 2-3 Tigres UANL *
| 26.05.2005 | Tigres UANL | 2-1 | Once Caldas | |
| 19.05.2005 | Once Caldas | 1-1 | Tigres UANL | |