*Boca Juniors 5-2 Club Atlas
| 22.05.2008 | Club Atlas | 0-3 | Boca Juniors | |
| 15.05.2008 | Boca Juniors | 2-2 | Club Atlas | |
*Club América 2-1 Santos/SP
| 23.05.2008 | Santos/SP | 1-0 | Club América | |
| 16.05.2008 | Club América | 2-0 | Santos/SP | |
San Lorenzo 2-2 LDU Quito *
| 23.05.2008 | LDU Quito | 1-1/p.5-3 | San Lorenzo | |
| 16.05.2008 | San Lorenzo | 1-1 | LDU Quito | |
São Paulo/SP 2-3 Fluminense/RJ *
| 22.05.2008 | Fluminense/RJ | 3-1 | São Paulo/SP | |
| 15.05.2008 | São Paulo/SP | 1-0 | Fluminense/RJ | |