*Boca Juniors 2-1 Fluminense/RJ
| 24.05.2012 | Fluminense/RJ | 1-1 | Boca Juniors | |
| 18.05.2012 | Boca Juniors | 1-0 | Fluminense/RJ | |
Club Libertad 2-2 Univ de Chile *
| 25.05.2012 | Univ de Chile | 1-1/p.5-3 | Club Libertad | |
| 17.05.2012 | Club Libertad | 1-1 | Univ de Chile | |
Vasco da Gama/RJ 0-1 Corinthians/SP *
| 24.05.2012 | Corinthians/SP | 1-0 | Vasco da Gama/RJ | |
| 17.05.2012 | Vasco da Gama/RJ | 0-0 | Corinthians/SP | |
Vélez Sársfield 1-1 Santos/SP *
| 25.05.2012 | Santos/SP | 1-0/p.4-2 | Vélez Sársfield | |
| 18.05.2012 | Vélez Sársfield | 1-0 | Santos/SP | |