AS Roma 0-4 Real Madrid *
| 08.03.2016 | Real Madrid | 2-0 | AS Roma | |
| 17.02.2016 | AS Roma | 0-2 | Real Madrid | |
Juventus FC 4-6 Bayern München *
| 16.03.2016 | Bayern München | 4-2 AET | Juventus FC | |
| 23.02.2016 | Juventus FC | 2-2 | Bayern München | |
Arsenal FC 1-5 FC Barcelona *
| 16.03.2016 | FC Barcelona | 3-1 | Arsenal FC | |
| 23.02.2016 | Arsenal FC | 0-2 | FC Barcelona | |
Dynamo Kyiv 1-3 Manchester City *
| 15.03.2016 | Manchester City | 0-0 | Dynamo Kyiv | |
| 24.02.2016 | Dynamo Kyiv | 1-3 | Manchester City | |
*Paris St. Germain 4-2 Chelsea FC
| 09.03.2016 | Chelsea FC | 1-2 | Paris St. Germain | |
| 16.02.2016 | Paris St. Germain | 2-1 | Chelsea FC | |
PSV Eindhoven 0-0 Atlético Madrid *
| 15.03.2016 | Atlético Madrid | 0-0/p.8-7 | PSV Eindhoven | |
| 24.02.2016 | PSV Eindhoven | 0-0 | Atlético Madrid | |
KAA Gent 2-4 VfL Wolfsburg *
| 08.03.2016 | VfL Wolfsburg | 1-0 | KAA Gent | |
| 17.02.2016 | KAA Gent | 2-3 | VfL Wolfsburg | |
*SL Benfica 3-1 Zenit
| 09.03.2016 | Zenit | 1-2 | SL Benfica | |
| 16.02.2016 | SL Benfica | 1-0 | Zenit | |