Vidi FC 2-3 AEK Athens *
| 28.08.2018 | AEK Athens | 1-1 | Vidi FC | |
| 22.08.2018 | Vidi FC | 1-2 | AEK Athens | |
*AFC Ajax 3-1 Dynamo Kyiv
| 28.08.2018 | Dynamo Kyiv | 0-0 | AFC Ajax | |
| 22.08.2018 | AFC Ajax | 3-1 | Dynamo Kyiv | |
*BSC Young Boys 3-2 Dinamo Zagreb
| 28.08.2018 | Dinamo Zagreb | 1-2 | BSC Young Boys | |
| 22.08.2018 | BSC Young Boys | 1-1 | Dinamo Zagreb | |
*FK Crvena Zvezda 2-2 RB Salzburg
| 29.08.2018 | RB Salzburg | 2-2 | FK Crvena Zvezda | |
| 21.08.2018 | FK Crvena Zvezda | 0-0 | RB Salzburg | |
BATE Borisov 2-6 PSV Eindhoven *
| 29.08.2018 | PSV Eindhoven | 3-0 | BATE Borisov | |
| 21.08.2018 | BATE Borisov | 2-3 | PSV Eindhoven | |
*SL Benfica 5-2 PAOK Salonica
| 29.08.2018 | PAOK Salonica | 1-4 | SL Benfica | |
| 21.08.2018 | SL Benfica | 1-1 | PAOK Salonica | |