KAA Gent 1-5 Dynamo Kyiv *
| 29.09.2020 | Dynamo Kyiv | 3-0 | KAA Gent | |
| 23.09.2020 | KAA Gent | 1-2 | Dynamo Kyiv | |
Molde FK 3-3 Ferencvaros TC *
| 29.09.2020 | Ferencvaros TC | 0-0 | Molde FK | |
| 23.09.2020 | Molde FK | 3-3 | Ferencvaros TC | |
*FK Krasnodar 4-2 PAOK Salonica
| 30.09.2020 | PAOK Salonica | 1-2 | FK Krasnodar | |
| 22.09.2020 | FK Krasnodar | 2-1 | PAOK Salonica | |
Maccabi Tel Aviv 2-5 RB Salzburg *
| 30.09.2020 | RB Salzburg | 3-1 | Maccabi Tel Aviv | |
| 22.09.2020 | Maccabi Tel Aviv | 1-2 | RB Salzburg | |
*Olympiakos Pireus 2-0 Omonia Nicosia
| 29.09.2020 | Omonia Nicosia | 0-0 | Olympiakos Pireus | |
| 23.09.2020 | Olympiakos Pireus | 2-0 | Omonia Nicosia | |
Slavia Praha 1-4 FC Midtjylland *
| 30.09.2020 | FC Midtjylland | 4-1 | Slavia Praha | |
| 22.09.2020 | Slavia Praha | 0-0 | FC Midtjylland | |