*Sheriff Tiraspol 3-0 Dinamo Zagreb
| 25.08.2021 | Dinamo Zagreb | 0-0 | Sheriff Tiraspol | |
| 17.08.2021 | Sheriff Tiraspol | 3-0 | Dinamo Zagreb | |
*BSC Young Boys 6-4 Ferencvaros TC
| 24.08.2021 | Ferencvaros TC | 2-3 | BSC Young Boys | |
| 18.08.2021 | BSC Young Boys | 3-2 | Ferencvaros TC | |
*Malmö FF 3-2 Ludogorets
| 24.08.2021 | Ludogorets | 2-1 | Malmö FF | |
| 18.08.2021 | Malmö FF | 2-0 | Ludogorets | |
*RB Salzburg 4-2 Brøndby IF
| 25.08.2021 | Brøndby IF | 1-2 | RB Salzburg | |
| 17.08.2021 | RB Salzburg | 2-1 | Brøndby IF | |