Linfield Belfast 2-4 CS Fola Esch *
| 12.08.2021 | CS Fola Esch | 2-1 | Linfield Belfast | |
| 03.08.2021 | Linfield Belfast | 1-2 | CS Fola Esch | |
*Riga FC 4-2 Hibernians Paola
| 12.08.2021 | Hibernians Paola | 1-4 AET | Riga FC | |
| 05.08.2021 | Riga FC | 0-1 | Hibernians Paola | |
KF Prishtina 2-3 FK Bodo/Glimt *
| 12.08.2021 | FK Bodo/Glimt | 2-0 | KF Prishtina | |
| 05.08.2021 | KF Prishtina | 2-1 | FK Bodo/Glimt | |
*Maccabi Haifa 7-3 HB Torshavn
| 12.08.2021 | HB Torshavn | 1-0 | Maccabi Haifa | |
| 05.08.2021 | Maccabi Haifa | 7-2 | HB Torshavn | |
*Shamrock Rovers 3-0 KF Teuta Durres
| 12.08.2021 | KF Teuta Durres | 0-2 | Shamrock Rovers | |
| 05.08.2021 | Shamrock Rovers | 1-0 | KF Teuta Durres | |