Rosenborg BK 1-2 AEK Larnaca *
| 25.08.2011 | AEK Larnaca | 2-1 | Rosenborg BK | |
| 18.08.2011 | Rosenborg BK | 0-0 | AEK Larnaca | |
*Besiktas JK 3-2 Alania Vladikavkaz
| 25.08.2011 | Alania Vladikavkaz | 2-0 | Besiktas JK | |
| 18.08.2011 | Besiktas JK | 3-0 | Alania Vladikavkaz | |
Bursaspor 3-4 Anderlecht *
| 25.08.2011 | Anderlecht | 2-2 | Bursaspor | |
| 18.08.2011 | Bursaspor | 1-2 | Anderlecht | |
Athletic Bilbao 0-0 Trabzonspor
| 25.08.2011 | Trabzonspor | CANC | Athletic Bilbao | |
| 18.08.2011 | Athletic Bilbao | 0-0 | Trabzonspor | |
*Austria Wien 3-2 Gaz Metan Medias
| 25.08.2011 | Gaz Metan Medias | 1-0 | Austria Wien | |
| 18.08.2011 | Austria Wien | 3-1 | Gaz Metan Medias | |
Aalesund FK 2-7 AZ Alkmaar *
| 25.08.2011 | AZ Alkmaar | 6-0 | Aalesund FK | |
| 18.08.2011 | Aalesund FK | 2-1 | AZ Alkmaar | |
FC Zestafoni 3-5 Club Brugge *
| 25.08.2011 | Club Brugge | 2-0 | FC Zestafoni | |
| 18.08.2011 | FC Zestafoni | 3-3 | Club Brugge | |
*Vorskla 5-3 Dinamo Bucuresti
| 25.08.2011 | Dinamo Bucuresti | 2-3 | Vorskla | |
| 18.08.2011 | Vorskla | 2-1 | Dinamo Bucuresti | |
*AEK Athens 2-1 Dinamo Tbilisi
| 25.08.2011 | Dinamo Tbilisi | 1-1 AET | AEK Athens | |
| 18.08.2011 | AEK Athens | 1-0 | Dinamo Tbilisi | |
FC Nordsjælland 1-2 Sporting Lisboa *
| 25.08.2011 | Sporting Lisboa | 2-1 | FC Nordsjælland | |
| 18.08.2011 | FC Nordsjælland | 0-0 | Sporting Lisboa | |
*Hannover 96 3-2 Sevilla FC
| 25.08.2011 | Sevilla FC | 1-1 | Hannover 96 | |
| 18.08.2011 | Hannover 96 | 2-1 | Sevilla FC | |
FK Ekranas 1-4 Hapoel Tel Aviv *
| 25.08.2011 | Hapoel Tel Aviv | 4-0 | FK Ekranas | |
| 18.08.2011 | FK Ekranas | 1-0 | Hapoel Tel Aviv | |
HJK Helsinki 3-6 Schalke 04 *
| 25.08.2011 | Schalke 04 | 6-1 | HJK Helsinki | |
| 18.08.2011 | HJK Helsinki | 2-0 | Schalke 04 | |
*Legia Warszawa 5-4 Spartak Moscow
| 25.08.2011 | Spartak Moscow | 2-3 | Legia Warszawa | |
| 18.08.2011 | Legia Warszawa | 2-2 | Spartak Moscow | |
Litex Lovech 1-3 Dynamo Kyiv *
| 25.08.2011 | Dynamo Kyiv | 1-0 | Litex Lovech | |
| 18.08.2011 | Litex Lovech | 1-2 | Dynamo Kyiv | |
*Lokomotiv Moscow 3-1 Spartak Trnava
| 25.08.2011 | Spartak Trnava | 1-1 | Lokomotiv Moscow | |
| 18.08.2011 | Lokomotiv Moscow | 2-0 | Spartak Trnava | |
*Metalist Kharkiv 4-0 FC Sochaux
| 25.08.2011 | FC Sochaux | 0-4 | Metalist Kharkiv | |
| 18.08.2011 | Metalist Kharkiv | 0-0 | FC Sochaux | |
Nacional Madeira 0-3 Birmingham City *
| 25.08.2011 | Birmingham City | 3-0 | Nacional Madeira | |
| 18.08.2011 | Nacional Madeira | 0-0 | Birmingham City | |
Omonia Nicosia 2-2 RB Salzburg *
| 25.08.2011 | RB Salzburg | 1-0 | Omonia Nicosia | |
| 18.08.2011 | Omonia Nicosia | 2-1 | RB Salzburg | |
*Maccabi Tel Aviv 4-2 Panathinaikos
| 25.08.2011 | Panathinaikos | 2-1 | Maccabi Tel Aviv | |
| 18.08.2011 | Maccabi Tel Aviv | 3-0 | Panathinaikos | |
*PAOK Salonica 3-1 Karpaty Lviv*
| 25.08.2011 | Karpaty Lviv* | 1-1 | PAOK Salonica | |
| 18.08.2011 | PAOK Salonica | 2-0 | Karpaty Lviv* | |
Differdange 0-6 Paris St. Germain *
| 25.08.2011 | Paris St. Germain | 2-0 | Differdange | |
| 18.08.2011 | Differdange | 0-4 | Paris St. Germain | |
*Lazio 9-1 Rabotnicki Skopje
| 25.08.2011 | Rabotnicki Skopje | 1-3 | Lazio | |
| 18.08.2011 | Lazio | 6-0 | Rabotnicki Skopje | |
*Maribor 3-2 Rangers FC
| 25.08.2011 | Rangers FC | 1-1 | Maribor | |
| 18.08.2011 | Maribor | 2-1 | Rangers FC | |
Śląsk Wrocław 2-4 Rapid Bucuresti *
| 25.08.2011 | Rapid Bucuresti | 1-1 | Śląsk Wrocław | |
| 18.08.2011 | Śląsk Wrocław | 1-3 | Rapid Bucuresti | |
*SC Braga 2-2 BSC Young Boys
| 25.08.2011 | BSC Young Boys | 2-2 | SC Braga | |
| 18.08.2011 | SC Braga | 0-0 | BSC Young Boys | |
*Shamrock Rovers 3-2 FK Partizan
| 25.08.2011 | FK Partizan | 1-2 AET | Shamrock Rovers | |
| 18.08.2011 | Shamrock Rovers | 1-1 | FK Partizan | |
*Slovan Bratislava 2-1 AS Roma
| 25.08.2011 | AS Roma | 1-1 | Slovan Bratislava | |
| 18.08.2011 | Slovan Bratislava | 1-0 | AS Roma | |
*FC Vaslui 2-1 Sparta Praha
| 25.08.2011 | Sparta Praha | 1-0 | FC Vaslui | |
| 18.08.2011 | FC Vaslui | 2-0 | Sparta Praha | |
FK Crvena Zvezda 1-6 Stade Rennais *
| 25.08.2011 | Stade Rennais | 4-0 | FK Crvena Zvezda | |
| 18.08.2011 | FK Crvena Zvezda | 1-2 | Stade Rennais | |
*Standard Liège 4-1 Helsingborg
| 25.08.2011 | Helsingborg | 1-3 | Standard Liège | |
| 18.08.2011 | Standard Liège | 1-0 | Helsingborg | |
*Steaua Bucuresti 3-1 CSKA Sofia
| 25.08.2011 | CSKA Sofia | 1-1 | Steaua Bucuresti | |
| 18.08.2011 | Steaua Bucuresti | 2-0 | CSKA Sofia | |
FC Thun 1-5 Stoke City *
| 25.08.2011 | Stoke City | 4-1 | FC Thun | |
| 18.08.2011 | FC Thun | 0-1 | Stoke City | |
SV Ried 0-5 PSV Eindhoven *
| 25.08.2011 | PSV Eindhoven | 5-0 | SV Ried | |
| 18.08.2011 | SV Ried | 0-0 | PSV Eindhoven | |
*Atlético Madrid 6-0 Vitória Guimarães
| 25.08.2011 | Vitória Guimarães | 0-4 | Atlético Madrid | |
| 18.08.2011 | Atlético Madrid | 2-0 | Vitória Guimarães | |