Anzhi Makhachkala 0-1 Newcastle United *
| 14.03.2013 | Newcastle United | 1-0 | Anzhi Makhachkala | |
| 07.03.2013 | Anzhi Makhachkala | 0-0 | Newcastle United | |
Steaua Bucuresti 2-3 Chelsea FC *
| 14.03.2013 | Chelsea FC | 3-1 | Steaua Bucuresti | |
| 07.03.2013 | Steaua Bucuresti | 1-0 | Chelsea FC | |
*SL Benfica 4-2 Girondins Bordeaux
| 14.03.2013 | Girondins Bordeaux | 2-3 | SL Benfica | |
| 07.03.2013 | SL Benfica | 1-0 | Girondins Bordeaux | |
*Tottenham 4-4 Inter Milan
| 14.03.2013 | Inter Milan | 4-1 AET | Tottenham | |
| 07.03.2013 | Tottenham | 3-0 | Inter Milan | |
Levante UD 0-2 Rubin Kazan *
| 14.03.2013 | Rubin Kazan | 2-0 AET | Levante UD | |
| 07.03.2013 | Levante UD | 0-0 | Rubin Kazan | |
VfB Stuttgart 1-5 Lazio *
| 14.03.2013 | Lazio | 3-1 | VfB Stuttgart | |
| 07.03.2013 | VfB Stuttgart | 0-2 | Lazio | |
Viktoria Plzen 1-2 Fenerbahçe SK *
| 14.03.2013 | Fenerbahçe SK | 1-1 | Viktoria Plzen | |
| 07.03.2013 | Viktoria Plzen | 0-1 | Fenerbahçe SK | |