*Arsenal FC 6-3 CSKA Moscow
| 12.04.2018 | CSKA Moscow | 2-2 | Arsenal FC | |
| 05.04.2018 | Arsenal FC | 4-1 | CSKA Moscow | |
*Atlético Madrid 2-1 Sporting Lisboa
| 12.04.2018 | Sporting Lisboa | 1-0 | Atlético Madrid | |
| 05.04.2018 | Atlético Madrid | 2-0 | Sporting Lisboa | |
Lazio 5-6 RB Salzburg *
| 12.04.2018 | RB Salzburg | 4-1 | Lazio | |
| 05.04.2018 | Lazio | 4-2 | RB Salzburg | |
RB Leipzig 3-5 Olympique Marseille *
| 12.04.2018 | Olympique Marseille | 5-2 | RB Leipzig | |
| 05.04.2018 | RB Leipzig | 1-0 | Olympique Marseille | |