AS Trenčín 1-4 AEK Larnaca *
| 30.08.2018 | AEK Larnaca | 3-0 | AS Trenčín | |
| 23.08.2018 | AS Trenčín | 1-1 | AEK Larnaca | |
*Olympiakos Pireus 4-2 Burnley
| 30.08.2018 | Burnley | 1-1 | Olympiakos Pireus | |
| 23.08.2018 | Olympiakos Pireus | 3-1 | Burnley | |
FC Basel 3-3 Apollon Limassol *
| 30.08.2018 | Apollon Limassol | 1-0 | FC Basel | |
| 23.08.2018 | FC Basel | 3-2 | Apollon Limassol | |
Atalanta Bergamo 0-0 FC København *
| 30.08.2018 | FC København | 0-0/p.4-3 | Atalanta Bergamo | |
| 23.08.2018 | Atalanta Bergamo | 0-0 | FC København | |
*Rapid Wien 4-3 FCSB
| 30.08.2018 | FCSB | 2-1 | Rapid Wien | |
| 23.08.2018 | Rapid Wien | 3-1 | FCSB | |
FK Partizan 1-4 Besiktas JK *
| 30.08.2018 | Besiktas JK | 3-0 | FK Partizan | |
| 23.08.2018 | FK Partizan | 1-1 | Besiktas JK | |
*Rangers FC 2-1 FK Ufa
| 30.08.2018 | FK Ufa | 1-1 | Rangers FC | |
| 23.08.2018 | Rangers FC | 1-0 | FK Ufa | |
KAA Gent 0-2 Girondins Bordeaux *
| 30.08.2018 | Girondins Bordeaux | 2-0 | KAA Gent | |
| 23.08.2018 | KAA Gent | 0-0 | Girondins Bordeaux | |
*Sarpsborg 08 4-3 Maccabi Tel Aviv
| 30.08.2018 | Maccabi Tel Aviv | 2-1 | Sarpsborg 08 | |
| 23.08.2018 | Sarpsborg 08 | 3-1 | Maccabi Tel Aviv | |
*Racing Genk 9-4 Brøndby IF
| 30.08.2018 | Brøndby IF | 2-4 | Racing Genk | |
| 23.08.2018 | Racing Genk | 5-2 | Brøndby IF | |
Sigma Olomouc 0-4 Sevilla FC *
| 30.08.2018 | Sevilla FC | 3-0 | Sigma Olomouc | |
| 23.08.2018 | Sigma Olomouc | 0-1 | Sevilla FC | |
Zorya Luhansk 2-3 RB Leipzig *
| 30.08.2018 | RB Leipzig | 3-2 | Zorya Luhansk | |
| 23.08.2018 | Zorya Luhansk | 0-0 | RB Leipzig | |